Results 31 to 40 of about 454 (211)

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

Advanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding, Songpeng Jia, Ran Meng, Xuelei Wang, Xiongfei Wu, Weiliang Shen, Yibo Zhang, Junquan Zhu   +7 more
wiley   +1 more source

The low sonic boom and aerodynamic optimization with trim constraint of supersonic jet

Hangkong gongcheng jinzhan
The abatement of sonic boom noise level is a decisive issue for supersonic transport of next generation. The low sonic boom optimization always make the configuration to a trend of higher swept and longer distribution of the wing along the fuselage，which
HAO Xuan, ZHANG Qingqing, SU Cheng, LIU Fang   +3 more
doaj   +1 more source

Low-Boom and Low-Drag Optimization of the Twin Engine Version of Silent Supersonic Business Jet

Journal of Fluid Science and Technology, 2008
Multi-Objective Optimization has been applied to a design problem of the twin engine concept for Silent Supersonic Business Jet (SSBJ). This problem aims to find main wing, body, tail wing and engine nacelle configurations, which can minimize both sonic ...
Koma SATO, Takayasu KUMANO, Masahito YONEZAWA, Hiroshi YAMASHITA, Shinkyu JEONG, Shigeru OBAYASHI   +5 more
doaj   +1 more source

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

Advanced Science, EarlyView.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang, Yu Geng, Xinyu Guo, Chen Wang, Yongjing Sun, Luqi Liu, Li Liu, QianQian Gao, XinFang Zhu, Hongxiang Cao, Gengshuo Zhang, Yunxia Liu, Guobin Zhang, Baoyin Chen, Jinfei Zhang, Xin Hou, Xiaoming Li, Dajian Zhang   +17 more
wiley   +1 more source

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways

Advanced Science, EarlyView.
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen, Bin Sun, Yajing Qiu, Chen Hua, Xiaoxi Lin, Wei Gao   +5 more
wiley   +1 more source

Near-Field Pressure Signature of New-Concept Supersonic Aircraft Obtained Using Open-Source Approach

Sci
This study investigates the numerical prediction of the sonic boom phenomenon in supersonic aircraft by evaluating the near-field pressure signatures of three different aeroshapes.
Antimo Glorioso, Francesco Petrosino, Mattia Barbarino, Giuseppe Pezzella   +3 more
doaj   +1 more source

Precise Localization of Single Rocket Debris Sonic Boom Sources Using TDOA and Particle Swarm Optimization [PDF]

ITM Web of Conferences
This paper addresses the precise localization of airborne sonic boom sources from rocket debris. A mathematical model utilizing Time Difference of Arrival (TDOA) technology is constructed to determine the exact location (longitude, latitude, altitude ...
Dong Lianan, Sun Zhen, Ning Jiaqing, Li Zetong   +3 more
doaj   +1 more source

Two different temporal domain integration schemes combined with compact finite difference method to solve modified Burgers’ equation

Ain Shams Engineering Journal, 2022
The modified Burgers’ equation has application in various fields such as explosions and sonic boom theory, propagation of torsional waves in thin circular viscoelastic rod, acoustic waves produced by laser radiations, etc.
Ravneet Kaur, Shallu, V.K. Kukreja, Nabendra Parumasur, Pravin Singh   +4 more
doaj   +1 more source

Adaptation of Echinococcus Multilocularis to Oxidative Stress Depends on EmPDK‐Mediated Metabolic Reprogramming

Advanced Science, EarlyView.
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang, Zhijian Xu, Ye Tian, Yao Zhang, Zhe Cheng, Yanhai Wang   +5 more
wiley   +1 more source

Discrete Adjoint Optimization Method for Low-Boom Aircraft Design Using Equivalent Area Distribution

Aerospace
This paper introduces a low-boom aircraft optimization design method guided by equivalent area distribution, which effectively improves the intuitiveness and refinement of inverse design. A gradient optimization method based on discrete adjoint equations
Chuang Ma, Jiangtao Huang, Daochun Li, Jun Deng, Gang Liu, Lin Zhou, Cheng Chen   +6 more
doaj   +1 more source