Results 131 to 140 of about 1,400 (162)

Ultrasound-excited temozolomide sonosensitization induces necroptosis in glioblastoma

Cancer Letters, 2023
Temozolomide (TMZ) has been determined to be the chemotherapeutic drug with efficacy for glioblastoma (GBM). Thus, potentiating the therapeutic effect of TMZ can undoubtedly yield twice the result with half the effort. In this study, we found for the first time that TMZ can produce reactive oxygen species (ROS) under the influence of ultrasound (US ...
Fanchen, Wang   +9 more
openaire   +2 more sources

Multifunctional sonosensitizers in sonodynamic cancer therapy

Chemical Society Reviews, 2020
Phototherapy, including photodynamic therapy and photothermal therapy, has the potential to treat several types of cancer.
Subin Son   +10 more
openaire   +2 more sources

Inorganic Sonosensitizers for Sonodynamic Therapy in Cancer Treatment

Small, 2023
AbstractThe rapid development of nanomedicine and nanobiotechnology has allowed the emergence of various therapeutic modalities with excellent therapeutic efficiency and biosafety, among which, the sonodynamic therapy (SDT), a combination of low‐intensity ultrasound and sonosensitizers, is emerging as a promising noninvasive treatment modality for ...
Xianshuo Cao   +5 more
openaire   +2 more sources

Titanium-based sonosensitizers for sonodynamic cancer therapy

Applied Materials Today, 2021
Abstract Sonodynamic therapy (SDT) is a new cancer treatment strategy that uses ultrasound (US) to trigger sonosensitizers to produce a large amount of reactive oxygen species (ROS) to kill malignant tumors, which features outstanding penetrating-depth in tissues and favorable outcome.
Yuqi Yang   +3 more
openaire   +1 more source

Erbium oxide nanoplates as a sonosensitizer devoid of photosensitivity

Chemical Communications, 2023
Er2O3 nanoplates could be a sensitizer for sonodynamic therapy without phototoxicity.
Yingfan Dai   +7 more
openaire   +2 more sources

Natural products in the discovery of novel sonosensitizers

Pharmacology & Therapeutics, 2016
Sonodynamic therapy (SDT), which involves a combination of low-intensity ultrasound and chemotherapeutic agents called sonosensitizers, has been developed for its promising, distinct advantages, such as its noninvasive nature relative to traditional surgery and radiotherapy, greater accessibility to treat deeply located diseases than photodynamic ...
Xin, Pang   +4 more
openaire   +2 more sources

Live bio-nano-sonosensitizer targets malignant tumors in synergistic therapy

Acta Biomaterialia, 2023
Sonosensitizers that can increase the concentration of reactive oxygen species (ROS) within a tumor microenvironment is a high priority for sonodynamic therapy (SDT). In this study, a functionalized, smart nanosonosensitizer based on Au-RuO2 nanoparticles (NPs) and selenium nanoparticles (Se NPs) that were electrostatically self-assembled onto the ...
Chenyang Yin   +10 more
openaire   +2 more sources

[Sonosensitizing Action of Teraphtal in Bacterial Media].

Biofizika, 2015
Employing bacterial model systems it was shown that the introduction of the soluble compound--sodium salt of cobalt octacarboxyphthalocyanine (teraphtal)--into the medium led in an ultrasonic field to a decrease in the proportion of survived bacteria.
S E, Mazina   +3 more
openaire   +3 more sources

Mitochondria-targeting sonosensitizer-loaded extracellular vesicles for chemo-sonodynamic therapy

Journal of Controlled Release, 2023
Sonodynamic therapy (SDT) has emerged as an effective therapeutic modality as it employs ultrasound (US) to eradicate deep-seated tumors noninvasively. However, the therapeutic efficacy of SDT in clinical settings remains limited owing to the low aqueous stability and poor pharmacokinetic properties of sonosensitizers.
Thuy Giang, Nguyen Cao   +9 more
openaire   +2 more sources

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