Results 21 to 30 of about 1,400 (162)

Sonosensitive MRI Nanosystems as Cancer Theranostics: A Recent Update [PDF]

Frontiers in Chemistry, 2018
In the tireless search for innovative and more efficient cancer therapies, sonosensitive Magnetic Resonance Imaging (MRI) agents play an important role. Basically, these systems consist of nano/microvesicles composed by a biocompatible membrane, responsive to ultrasound-induced thermal or mechanical effects, and an aqueous core, filled up with a MRI ...
Garello, Francesca, Terreno, Enzo
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Synergistic Efficacy of Ultrasound, Sonosensitizers and Chemotherapy: A Review [PDF]

Therapeutic Delivery, 2017
Chemotherapeutic agents, either in the form of systemically injected free drug or encapsulated in nanoparticles transport vehicles, must overcome three main obstacles prior to reaching and interacting with their intended target inside tumor cells.
Hirschberg, Henry, Madsen, Steen J
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PFOB sonosensitive microdroplets: determining their interaction radii with focused ultrasound using MR thermometry and a Gaussian convolution kernel computation

International Journal of Hyperthermia, 2022
Purpose: Micron-sized perfluorocarbon droplet adjuvants to focused ultrasound therapies allow lower applied power, circumvent unwanted prefocal heating, and enhance thermal dose in highly perfused tissues.
Ryan Holman, Laura Gui, Orane Lorton, Pauline Guillemin, Stéphane Desgranges, Christiane Contino-Pépin, Rares Salomir   +6 more
doaj   +1 more source

Single Atom Iron‐Doped Graphic‐Phase C3N4 Semiconductor Nanosheets for Augmented Sonodynamic Melanoma Therapy Synergy with Endowed Chemodynamic Effect

Advanced Science, 2023
Sonodynamic therapy (SDT) is a non‐invasive therapeutic modality with high tissue‐penetration depth to induce reactive oxygen species (ROS) generation for tumor treatment.
Guiying Feng, Hui Huang, Min Zhang, Zhuole Wu, Dandan Sun, Qiqing Chen, Dayan Yang, Yuanyi Zheng, Yu Chen, Xiangxiang Jing   +9 more
doaj   +1 more source

Perfluorocarbon emulsion enhances MR-ARFI displacement and temperature in vitro: Evaluating the response with MRI, NMR, and hydrophone

Frontiers in Oncology, 2023
Sonosensitive perfluorocarbon F8TAC18-PFOB emulsion is under development to enhance heating, increase thermal contrast, and reduce treatment times during focused ultrasound tumor ablation of highly perfused tissue. The emulsion previously showed enhanced
Ryan Holman, Orane Lorton, Pauline C. Guillemin, Stéphane Desgranges, Francesco Santini, Davide Bernardo Preso, Mohamed Farhat, Christiane Contino-Pépin, Rares Salomir, Rares Salomir   +9 more
doaj   +1 more source

Piezotronic and piezo‐phototronic effects on sonodynamic disease therapy

BMEMat, 2023
With the development of engineered nanomaterials and nanomedicines, utilization of nanomaterials to generate excessive reactive oxygen species under exogenous ultrasound (US) irradiation for realizing disease therapy, namely sonodynamic therapy (SDT ...
Yunchao Zhao, Tian Huang, Xiaodi Zhang, Yuanbo Cui, Lili Zhang, Linlin Li, Zhong Lin Wang   +6 more
doaj   +1 more source

Ultrathin‐FeOOH‐Coated MnO2 Sonosensitizers with Boosted Reactive Oxygen Species Yield and Remodeled Tumor Microenvironment for Efficient Cancer Therapy

Advanced Science, 2022
Sonodynamic therapy (SDT) typically suffers from compromised anticancer efficacy owing to the low reactive oxygen species (ROS) yield and complicated tumor microenvironment (TME) which can consume ROS and support the occurrence and development of tumors.
Qiyu Liu, Liyin Shi, Ying Liao, Xianshuo Cao, Xiaoqing Liu, Yanxia Yu, Zifan Wang, Xihong Lu, Jianwei Wang   +8 more
doaj   +1 more source

A Comprehensive Review of Inorganic Sonosensitizers for Sonodynamic Therapy

International Journal of Molecular Sciences, 2023
Sonodynamic therapy (SDT) is an emerging non-invasive cancer treatment method in the field of nanomedicine, which has the advantages of deep penetration, good therapeutic efficacy, and minimal damage to normal tissues. Sonosensitizers play a crucial role in the process of SDT, as their structure and properties directly determine the treatment outcome ...
Peng Chen, Ping Zhang, Navid Hussain Shah, Yanyan Cui, Yaling Wang   +4 more
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Enhancement of HIFU thermal therapy in perfused tissue models using micron-sized FTAC-stabilized PFOB-core endovascular sonosensitizers

International Journal of Hyperthermia, 2020
Background High intensity focused ultrasound (HIFU) is clinically accepted for the treatment of solid tumors but remains challenging in highly perfused tissue due to the heat sink effect.
Orane Lorton, Pauline C. Guillemin, Ryan Holman, Stéphane Desgranges, Laura Gui, Lindsey A. Crowe, Sylvain Terraz, Antonio Nastasi, François Lazeyras, Christiane Contino-Pépin, Rares Salomir   +10 more
doaj   +1 more source

Ferroptosis promotes sonodynamic therapy: a platinum(ii)–indocyanine sonosensitizer

Chemical Science, 2022
A novel platinum(ii)–cyanine complex showed a greater excellent sonodynamic therapeutic effect than photodynamic therapy in vivo. This work expands the biological applications of metal complexes from traditional photodynamic therapy to sonodynamic therapy.
Yidan Lai, Nong Lu, Ai Ouyang, Qianling Zhang, Pingyu Zhang   +4 more
openaire   +2 more sources