Results 71 to 80 of about 3,675 (170)

Bringing non-human primate research into the post-genomic era: how monkeys are teaching us about elite controllers of HIV/AIDS [PDF]

, 2014
Whole-genome sequencing of Mauritian cynomolgus macaques reveals novel candidate loci for controlling simian immunodeficiency virus replication.
Vallender, Eric J
core   +1 more source

Fc gamma receptors: Their evolution, genomic architecture, genetic variation, and impact on human disease

Immunological Reviews, Volume 328, Issue 1, Page 65-97, November 2024.
Summary Fc gamma receptors (FcγRs) are a family of receptors that bind IgG antibodies and interface at the junction of humoral and innate immunity. Precise regulation of receptor expression provides the necessary balance to achieve healthy immune homeostasis by establishing an appropriate immune threshold to limit autoimmunity but respond effectively ...
Sarah Frampton, Rosanna Smith, Lili Ferson, Jane Gibson, Edward J. Hollox, Mark S. Cragg, Jonathan C. Strefford   +6 more
wiley   +1 more source

Identification of a novel retroviral gene unique to human immunodeficiency virus type 2 and simian immunodeficiency virus SIVMAC [PDF]

, 1988
Human and simian immunodeficiency-associated retroviruses are extraordinarily complex, containing at least five genes, tat, art, sor, R, and 3' orf, in addition to the structural genes gag, pol, and env.
Hahn, Beatrice H., Hood, Leroy E., Jameson, Bradford A., Kappes, John C., Kent, Stephen B. H., Lee, Shei-Wen, Morrow, Casey D., Shaw, George M.   +7 more
core  

Species-Specific Activity of HIV-1 Vpu and Positive Selection of Tetherin Transmembrane Domain Variants [PDF]

, 2011
Tetherin/BST-2/CD317 is a recently identified antiviral protein that blocks the release of nascent retrovirus, and other virus, particles from infected cells. An HIV-1 accessory protein, Vpu, acts as an antagonist of tetherin. Here, we show that positive
Bartlett, Mackenzie, Bieniasz, Paul D., Fofana, Ismael Farouck, Hatziioannou, Theodora, Johnson, Welkin Eric, McNatt, Matthew W., Neil, Stuart J. D., Zang, Trinity   +7 more
core   +1 more source

Adaptive evolution and functional significance of the PPARGC1A gene across diverse animal species

Ecology and Evolution, Volume 14, Issue 10, October 2024.
This study conducts codon‐based analyses of the PPARGC1A gene across 38 vertebrate species, revealing distinct patterns of evolutionary change. Positive selection pressures were observed at specific codon sites, particularly 4, 11, 66, and 123, with codon 137 displaying the most pronounced selective advantage.
Seyed Mahdi Hosseini, Farman Ullah, Muhammad Zulfiqar Ahmad, Majid Pasandideh, Aixin Liang, Guohua Hua, Liguo Yang   +6 more
wiley   +1 more source

What animals do not do or fail to find: A novel observational approach for studying cognition in the wild [PDF]

, 2019
To understand how our brain evolved and what it is for, we are in urgent need of knowledge about the cognitive skills of a large variety of animal species and individuals, and their relationships to rapidly disappearing social and ecological conditions ...
Janmaat, K.
core   +1 more source

The establishment of a collaborative surveillance program with indigenous hunters to characterize primate health in Southern Guyana

American Journal of Primatology, Volume 86, Issue 6, June 2024.
Picture from a workshop conducted with Waiwai parabiologists (Left to right: Suse, Marawanaru, Shoni) and veterinarian (Milstein) to develop culturally appropriate sampling methodology. Parabiologists shared their thoughts on which tissues they could feasibly collect in ways that would not interfere with normal hunting and butchery practices. Here, the
Marissa S. Milstein, Christopher A. Shaffer, Phillip Suse, Elisha Marawanaru, Romel Shoni, Steven Suse, Bemner Issacs, Peter A. Larsen, Dominic A. Travis, Karen A. Terio, Tiffany M. Wolf   +10 more
wiley   +1 more source

Role of HLA Adaptation in HIV Evolution [PDF]

, 2016
Killing of HIV-infected cells by CD8(+) T-cells imposes strong selection pressure on the virus toward escape. The HLA class I molecules that are successful in mediating some degree of control over the virus are those that tend to present epitopes in ...
Alasdair Leslie, Henrik N. Kløverpris, Philip Goulder   +2 more
core   +1 more source

The effects of feeding frequency on jaw loading in two lemur species

American Journal of Biological Anthropology, Volume 184, Issue 1, May 2024.
Abstract Objectives Studies on oral processing are often snapshots of behaviors that examine feeding through individual bouts. In this study, we expand on our previous work comparing bite/chew variables per feeding bout to summed daily biting, chewing, and food intake to interpret loading that could have potential morphological effects.
Nayuta Yamashita, Nina Flowers, Mariana Dutra Fogaça   +2 more
wiley   +1 more source

Design of multi‐epitope chimeric vaccine against Monkeypox virus and SARS‐CoV‐2: A vaccinomics perspective

Journal of Cellular and Molecular Medicine, Volume 28, Issue 10, May 2024.
Abstract The current era we experience is full with pandemic infectious agents that no longer threatens the major local source but the whole globe. Almost the most emerging infectious agents are severe acute respiratory syndrome coronavirus‐2 (SARS CoV‐2), followed by monkeypox virus (MPXV).
Haitham Al‐Madhagi, Adeela Kanawati, Zaher Tahan   +2 more
wiley   +1 more source