Results 121 to 130 of about 69,730 (299)

Shikimate pathway disruption in yeast induces metabolite self‐assembly into toxic aggregates

open access: yesThe FEBS Journal, EarlyView.
In Saccharomyces cerevisiae, shikimate pathway disruption induces toxic metabolite assemblies. Deleting ARO4 plus phenylalanine (Phe) feeding causes Phenylalanine accumulation, lowers ARO3 activity, and triggers amyloid‐like fibril formation. Deleting ARO3 plus tyrosine (Tyr) feeding leads to Tyrosine buildup and similar fibril assembly.
Hanaa Adsi   +6 more
wiley   +1 more source

Osmolytes as Mediators of the Muscle Tissue’s Responses to Inflammation: Emerging Regulators of Myositis with Therapeutic Potential

open access: yesEuropean Medical Journal Rheumatology, 2017
Chronic inflammation of skeletal muscle tissues, termed myositis, is associated with inherited muscular dystrophy and acquired inflammatory myopathy.
Boel De Paepe
doaj  

Fractal aspects of sorbitol flow. [PDF]

open access: yes, 2016
The size and shape of bulk solid particles is an important factor which affects its flow and consolidation behaviour. In this thesis, the properties of sorbitol size fractions ranging from 80 to 500 µm were studied by using helium pycnometry, optical ...
Dvořáková, Klára
core  

Sorbitol synthesis by an engineered Lactobacillus casei strain expressing a sorbitol-6-phosphate dehydrogenase gene within the lactose operon

open access: yes, 2005
Sorbitol is claimed to have important health-promoting effects and Lactobacillus casei is a lactic acid bacterium relevant as probiotic and used as a cheese starter culture. A sorbitol-producing L. casei strain might therefore be of considerable interest
Perez Martinez Gaspar   +2 more
core   +1 more source

Contrasting effects of different molecular crowding environments on base‐pair opening/closing dynamics of DNA triplex structures

open access: yesThe FEBS Journal, EarlyView.
Base‐pair opening and closing regulate nucleic‐acid structure, stability, and function, but how these motions behave under intracellular molecular crowding remains unclear. Using NMR, we quantified these dynamics in a DNA triplex under two crowder‐reconstituted environments that mimic cellular crowding.
Tomoki Sakamoto   +3 more
wiley   +1 more source

Analysis of Thermal and Crystallization in Cryoprotective Agents

open access: yesZhileng xuebao, 2014
Ice crystal formation is one of the factors that causes cell damage during crvopreservation process.Ice crystal will provide fundamental information for the development of appropriate cryopreservation protocols.Effects of concentration and properties of ...
Yang Bo   +3 more
doaj  

Phenotypic characterization of Arabidopsis thaliana mutants that alleviate root growth defects in a vitamin B6 biosynthesis mutant

open access: yesThe FEBS Journal, EarlyView.
Vitamin B6 is a critical molecule for plant metabolism and development. Rsr4‐1, a loss‐of‐function mutant in a vitamin B6 biosynthesis gene, has a distinct short root phenotype. Here we describe five novel suppressor mutants with an rsr4‐1 background that have normalized root growth and distinct phenotypic and molecular characteristics, representing a ...
Marcelina Parra   +4 more
wiley   +1 more source

Studies on sorbitol dehydrogenase in acetobacter suboxydans [PDF]

open access: yes, 2018
A chemically defined medium containing no amino acids supported cellular growth of A. suboxydans NCIB 9108. The effectiveness of selected carbon sources for the growth of the organism in a carbohydrate / salts medium was investigated.
Al-Amari, Ahmed Lotf
core  

Formation of sorbitol by Zymomonas mobilis

open access: yes, 1984
Sorbitol is formed as the major by-product in ethanol fermentations by Zymomonas mobilis when both glucose and fructose are present in the fermentation medium. The amount of sorbitol produced was equivalent to as much as 11% of the original carbon source,
Viikari, Liisa
core   +1 more source

Methods to Study Mitochondrial Metabolism and Homeostasis in Fission Yeast

open access: yes
Yeast, EarlyView.
Ferran Gómez‐Armengol   +2 more
wiley   +1 more source

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