Results 121 to 130 of about 8,616,866 (238)

Familial Co‐Aggregation of Neurodevelopmental Conditions and Childhood‐Onset Type 1 Diabetes

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Childhood‐onset Type 1 diabetes (T1D) is associated with neurodevelopmental conditions (NDCs). We examined whether this association extends to relatives and assessed phenotypic, genetic, and environmental correlations between T1D and NDCs.
Shengxin Liu   +12 more
wiley   +1 more source

Afamelanotide improves quality of life and light tolerance in Austrian erythropoietic protoporphyria patients

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Erythropoietic protoporphyria (EPP) is a rare genetic disorder characterized by severe phototoxic reactions that occur within minutes of light exposure. In clinical studies, afamelanotide has been shown to prolong pain‐free sun exposure, improve quality of life, and reduce the frequency and severity of phototoxic reactions ...
Magdalena Seidl‐Philipp   +9 more
wiley   +1 more source

Numerical investigation of MHD flow with Soret and Dufour effect

open access: yes, 2018
This paper describes the flow due to an exponentially curved surface subject to Soret and Dufour effects. Nonlinear velocity is considered. Exponentially curved stretchable sheet induced the flow.
Muhammad Ijaz Khan   +3 more
core   +1 more source

PEG400 regulates Falcipain 2 activity through an allosteric mechanism

open access: yesThe FEBS Journal, EarlyView.
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath   +2 more
wiley   +1 more source

Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes

open access: yesThe FEBS Journal, EarlyView.
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb   +4 more
wiley   +1 more source

First results of Soret coefficient measurement experiment

open access: yes, 1995
The scope of the Soret Coefficient Measurement Experiment (SCM) is to measure the Soret coefficient in 20 binary organic mixtures and aqueous solutions.
Dupin, Jean-Charles   +2 more
core   +1 more source

Jacques Maritain, Maurice Blondel, and the Ends of Art

open access: yesModern Theology, EarlyView.
Abstract This article reconsiders Jacques Maritain's philosophical poetics by situating it within his longstanding debate with Maurice Blondel over the nature and unity of intellect. I argue that Maritain's influential defence of artistic autonomy, first articulated in Art et scolastique (1920), is ultimately unsound.
Steven Toussaint
wiley   +1 more source

The State of the Art of Bernstein's Problem

open access: yes, 2005
Wether the only minimal stable complete hypersurfaces in R^{n+1}, with 2< n < 8 are hyperplanes, is an open problem.
NELLI, BARBARA, SORET M.
core  

Inhibition of P‐glycoprotein using photoimmunotherapy in peritoneal metastasis mouse model

open access: yesPhotochemistry and Photobiology, EarlyView.
Photoimmunotherapy (PIT) using photoimmunoconjugates (PICs) can inhibit the function of the ATP‐binding cassette (ABC) transporter P‐glycoprotein (P‐gp) in a mouse model of peritoneal carcinomatosis. Sterile‐filtered PIC was administered in vivo via intraperitoneal (IP) injection 20 days after IP tumor cell implantation of P‐gp‐overexpressing NCI/ADR ...
Kaitlyn A. Moore   +6 more
wiley   +1 more source

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