Results 91 to 100 of about 7,954 (200)
Jacques Maritain, Maurice Blondel, and the Ends of Art
Abstract This article reconsiders Jacques Maritain's philosophical poetics by situating it within his longstanding debate with Maurice Blondel over the nature and unity of intellect. I argue that Maritain's influential defence of artistic autonomy, first articulated in Art et scolastique (1920), is ultimately unsound.
Steven Toussaint
wiley +1 more source
Inhibition of P‐glycoprotein using photoimmunotherapy in peritoneal metastasis mouse model
Photoimmunotherapy (PIT) using photoimmunoconjugates (PICs) can inhibit the function of the ATP‐binding cassette (ABC) transporter P‐glycoprotein (P‐gp) in a mouse model of peritoneal carcinomatosis. Sterile‐filtered PIC was administered in vivo via intraperitoneal (IP) injection 20 days after IP tumor cell implantation of P‐gp‐overexpressing NCI/ADR ...
Kaitlyn A. Moore +6 more
wiley +1 more source
A low‐cost handheld device for monitoring cutaneous photosensitivity
The cutaneous photosensitivity detection (CPD) device is a handheld contact‐based measurement device using 405 nm excitation and red fluorescence detection for monitoring skin phototoxicity risk after photodynamic therapy (PDT) procedures involving systemic aminolaevulinic acid (ALA) induced protoporphyrin IX (PpIX) photosensitization.
Md Asaduzzaman Rasel +4 more
wiley +1 more source
Effect of HBr on Explosion Limits of Stoichiometric Hydrogen‐oxygen Mixture
ABSTRACT This work, based on numerical simulations, discusses the effect of HBr as an inhibitor on the explosion limit of stoichiometric hydrogen‐oxygen gas mixture in a closed spherical vessel. The numerical simulation solves the complete governing equations for mass, momentum, species and energy.
Chunkan Yu, Peter Glarborg
wiley +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
The particle with high surface hydrophilicity exhibits strong thermophoretic attraction, as its dense hydration layer enhances the role of interfacial water molecules in determining thermophoretic mobility over other ionic effects. This finding elucidates the mechanism underlying the robust thermophoretic accumulation of Escherichia coli in high ...
Seungyeop Kang +3 more
wiley +1 more source
Competing Pathways in Heme Catalyzed Oxidations With Porphyrin‐Centered Reactivity
Heme‐catalyzed oxidations proceeding through porphyrin‐centered reactivity are quite rare. In attempts to optimize the catalytic umpolung of chloride proceeding via an isoporphyrin, we found a competing pathway. The iron(III) π‐dication readily performs alternative reactivity, leading to a bifurcation in reaction mechanisms at this point.
Silène Engbers +3 more
wiley +1 more source
Miniaturized Droplet‐Based Adaptation of the Ames Test for High‐Throughput Mutagenicity Assessment
ABSTRACT This work presents the first demonstration of a tube‐based droplet microfluidic implementation of the Ames test, bridging single‐droplet resolution with regulatory genotoxicity testing. The Ames test is a cornerstone assay for detecting mutagenicity, but conventional plate‐ and well‐based formats suffer from high reagent consumption, low ...
Jialan Cao +3 more
wiley +1 more source
This study demonstrates that combination BL and 5‐ALA PDT does not induce detectable levels of CPD or 6–4PP photolesions in human dermal fibroblasts in vitro. Our findings contribute to the lesion‐specific genotoxic safety profile of blue light photodynamic therapy, an established research topic.ABSTRACTPhotodynamic therapy (PDT) is an established ...
Julia Stolyar +3 more
wiley +1 more source
Photocatalytic Hydrogen Evolution From Self‐Assembled Stacks of Pd–TCPP and Pt–TCPP
ABSTRACT The present work demonstrates that surfactant‐free precipitation of Pd– and Pt–TCPP in MeOH/H2O yields well‐defined supramolecular architectures (µm‐long nanorods) whose photocatalytic function tracks their metal‐dependent photophysics and stacking.
Jihyeon Kim +3 more
wiley +1 more source

