Results 101 to 110 of about 10,800,271 (244)

Influence of heme and pH on the oligomeric states of Brucella melitensis bacterioferritin

Acta Crystallographica Section D, EarlyView.
The oligomerization of B. melitensis bacterioferritin (BmBfr) was studied using X‐ray crystallography, size‐exclusion chromatography and thermal shift analysis. These techniques allowed the characterization of both apo and holo BmBfr, highlighting the impact of heme and pH on the oligomerization mechanism.Bacterioferritin from Brucella melitensis ...
Tanguy Scaillet, Clément Champagne, Johan Wouters   +2 more
wiley   +1 more source

Multiphysics Finite Element Analysis of Diffusive–Bioconvective MHD Hybrid Nanofluid Flow Over an Exponentially Stretching Sheet

Advances in Mathematical Physics
This study examines the diffusive–bioconvective magnetohydrodynamic (MHD) flow of a hybrid nanofluid past an exponentially stretching sheet embedded in a porous medium, incorporating thermal radiation, viscous dissipation, Soret–Dufour effects, and ...
Paul M. Matao, L. Joseph Sademaki
doaj   +1 more source

Soret and Dufour effects on free convective heat and solute transfer in fluid saturated inclined porous cavity

Engineering Science and Technology, an International Journal, 2015
The present problem addresses double diffusive free convection in an inclined square cavity filled with fluid saturated porous medium under the influence of Soret and Dufour effects. The inclined cavity makes an angle with the horizontal plane.
Chandra Shekar Balla, Kishan Naikoti
doaj   +1 more source

Training and validation of an automated algorithm to differentiate no and minimal diabetic retinopathy from more severe stages in wide‐field images

Acta Ophthalmologica, EarlyView.
Abstract Purpose Diabetic retinopathy (DR) is a leading cause of blindness in the working‐age population. Screening is essential to identify and treat sight‐threatening stages prior to irreversible visual loss. This study aimed to train and validate an automated algorithm to identify no or minimal DR, potentially saving resources for specialist ...
Lars Morten Skollerud, Jakob Kristian Andersen, Sebastian Dinesen, Thiusius Rajeeth Savarimuthu, Jakob Grauslund   +4 more
wiley   +1 more source

Afamelanotide improves quality of life and light tolerance in Austrian erythropoietic protoporphyria patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Erythropoietic protoporphyria (EPP) is a rare genetic disorder characterized by severe phototoxic reactions that occur within minutes of light exposure. In clinical studies, afamelanotide has been shown to prolong pain‐free sun exposure, improve quality of life, and reduce the frequency and severity of phototoxic reactions ...
Magdalena Seidl‐Philipp, Hanna Schratter, Johanna Auer, Gerold Schwantzer, Maximilian Lammer, Philipp Hinteregger, Ines Vergeiner, Robert Gruber, Peter Wolf, Angelika Hofer   +9 more
wiley   +1 more source

PEG400 regulates Falcipain 2 activity through an allosteric mechanism

The FEBS Journal, EarlyView.
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath, Subhoja Chakraborty, Sampa Biswas   +2 more
wiley   +1 more source

Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes

The FEBS Journal, EarlyView.
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb, Dominik Hörtnagel, Chris Oostenbrink, Paul G. Furtmüller, Stefan Hofbauer   +4 more
wiley   +1 more source

Student–teacher relationships as a mediator of children's education‐linked genetics: results from the Norwegian Mother, Father and Child Cohort Study

Journal of Child Psychology and Psychiatry, EarlyView.
Background Genetic differences are robustly associated with educational outcomes, but how they become linked is poorly understood. A plausible hypothesis, yet to be thoroughly empirically tested, is that the school environment mediates the association. Methods Using structural equation models, we tested whether the student–teacher relationship at age 5
Chloe Austerberry, Elizabeth C. Corfield, Alexandra Havdahl, Dinka Smajlagic, Ragnhild Eek Brandlistuen, Mari Vaage Wang, Laurel Fish, Marialivia Bernardi, Jessica van de Grint‐Stoop, Mona Bekkhus, Pasco Fearon   +10 more
wiley   +1 more source

(Ultra)high‐Pressure Metamorphism in Sedimentary Versus Basaltic Rocks: Insights From a Variscan Mélange in the South Carpathians

Journal of Metamorphic Geology, EarlyView.
ABSTRACT Reconstructing the pressure–temperature–time (P–T–t) evolution of (ultra)high‐pressure rocks is essential for constraining subduction and collisional dynamics. Subduction zones are often investigated using basic eclogites, whereas nonbasic high‐pressure rocks remain comparatively understudied, potentially hindering a comprehensive ...
Otavio S. G. Silva, Bruno V. Ribeiro, Gavril Săbău, Fabricio Caxito, Paulo A. de Paiva‐Silva, Pierre Lanari, George Luvizotto, Mahyra Tedeschi   +7 more
wiley   +1 more source

Jacques Maritain, Maurice Blondel, and the Ends of Art

Modern Theology, EarlyView.
Abstract This article reconsiders Jacques Maritain's philosophical poetics by situating it within his longstanding debate with Maurice Blondel over the nature and unity of intellect. I argue that Maritain's influential defence of artistic autonomy, first articulated in Art et scolastique (1920), is ultimately unsound.
Steven Toussaint
wiley   +1 more source