Results 111 to 120 of about 8,623,807 (207)
Summary Background Erythropoietic protoporphyria (EPP) is a rare genetic disorder characterized by severe phototoxic reactions that occur within minutes of light exposure. In clinical studies, afamelanotide has been shown to prolong pain‐free sun exposure, improve quality of life, and reduce the frequency and severity of phototoxic reactions ...
Magdalena Seidl‐Philipp +9 more
wiley +1 more source
PEG400 regulates Falcipain 2 activity through an allosteric mechanism
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath +2 more
wiley +1 more source
The State of the Art of Bernstein's Problem
Wether the only minimal stable complete hypersurfaces in R^{n+1}, with 2< n < 8 are hyperplanes, is an open problem.
NELLI, BARBARA, SORET M.
core
First results of Soret coefficient measurement experiment
The scope of the Soret Coefficient Measurement Experiment (SCM) is to measure the Soret coefficient in 20 binary organic mixtures and aqueous solutions.
Dupin, Jean-Charles +2 more
core +1 more source
Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb +4 more
wiley +1 more source
Solvent intercalation disrupts the stacking order of protonated porphyrin‐based 2D COF nanoparticles, resulting in a less compactly packed structure with increased accessibility of porphyrin sites. This structural modulation leads to significantly enhanced chemiresistive NO2 sensing performance.
Yu Pan +4 more
wiley +2 more sources
Abstract Far‐red light (FRL) cyanobacteria occupy spectrally filtered habitats where visible wavelengths are depleted but far‐red radiation persists. Shark Bay (Western Australia) stromatolitic microbial mats provide such a habitat, containing subsurface cyanobacterial communities in which chlorophyll d/f (Chl d/f)‐containing phototrophs coexist with ...
Anya Salih +7 more
wiley +1 more source
The intricate dynamics of mixed convective thermic and species transport in a power-law flowing fluid through a continuously stretched surface are investigated. The uniqueness of this study lies in the consideration of fluid variable thermic conductivity
T. S. Khaleque +5 more
doaj +1 more source
Jacques Maritain, Maurice Blondel, and the Ends of Art
Abstract This article reconsiders Jacques Maritain's philosophical poetics by situating it within his longstanding debate with Maurice Blondel over the nature and unity of intellect. I argue that Maritain's influential defence of artistic autonomy, first articulated in Art et scolastique (1920), is ultimately unsound.
Steven Toussaint
wiley +1 more source
Inhibition of P‐glycoprotein using photoimmunotherapy in peritoneal metastasis mouse model
Photoimmunotherapy (PIT) using photoimmunoconjugates (PICs) can inhibit the function of the ATP‐binding cassette (ABC) transporter P‐glycoprotein (P‐gp) in a mouse model of peritoneal carcinomatosis. Sterile‐filtered PIC was administered in vivo via intraperitoneal (IP) injection 20 days after IP tumor cell implantation of P‐gp‐overexpressing NCI/ADR ...
Kaitlyn A. Moore +6 more
wiley +1 more source

