Results 111 to 120 of about 30,121,245 (253)
Use of Internet, e-mail and other IT resources
, 2008 Title from PDF caption (viewed on Nov. 16, 2010).; "This policy replaces all previously released memoranda and specifically obsoletes Ohio IT Policy ITP-E.8, "Limitations on the Use of Publicly Owned Hardware and Software," which had an effective date of
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Registration of Internet domain names
, 2005 Title from caption of PDF document (viewed Sept. 23, 2005).; "Effective: 08/26/2005."; Harvested from the web on 9/23/05Provides requirements for how agencies obtain and safeguard certain Internet domain names by establishing naming requirements, and a ...
Ohio. Statewide IT Policy. Investment and Governance Division
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FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
, 1969 Woman looking at The Dance II (1932), signed "Henri Matisse, Nice 1932". Studio Under the Eaves (1903); Matisse’s words over, "When I started to paint, I felt transported into a sort of paradise…" Interior with a Top Hat (1896). Seascape. Dinner Table
core +3 more sources
Cancer Research, Statistics, and TreatmentBackground: The role of induction chemotherapy (ICT) in locally advanced oropharyngeal and hypopharyngeal squamous cell carcinoma (SCC) remains debated, particularly in resource-limited settings.
Subramanian Vijayakanth +7 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source