Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Tuberculosis preventive therapy in Sierra Leone: early implementation gaps and lessons learned. [PDF]
Farma-Grant L +17 more
europepmc +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Oncologist and General Practitioner Perspectives of Telehealth-Delivered Colorectal Cancer Survivorship Care. [PDF]
Lisy K +9 more
europepmc +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
ECE-VDTDA: A robust and computationally efficient collision avoidance system for driver assistance in foggy weather. [PDF]
Raza N +7 more
europepmc +1 more source
Motivations of patients with dentofacial deformities seeking orthognathic treatment: an application of Q methodology. [PDF]
Cao K +5 more
europepmc +1 more source
Empirical Evaluation of Unoptimized Sorting Algorithms on 8-Bit AVR Arduino Microcontrollers. [PDF]
Golonka J, Krużel F.
europepmc +1 more source
Patient and clinician acceptability of an integrated physiotherapy and nutrition intervention after ICU discharge: a qualitative exploration of a pre-specified co-primary feasibility outcome of the PHOENIX trial. [PDF]
King E +9 more
europepmc +1 more source

