Results 71 to 80 of about 395,933 (237)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Can we apply accelerator-cores to control-intensive programs? [PDF]

open access: yes, 2009
There is a trend towards using accelerators to increase performance and energy efficiency of general-purpose processors. So far, most accelerators have been build with HPC-applications in mind.
De Bosschere, Koen   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

In Support of Huber [PDF]

open access: yes, 1992
The author takes exception to two recent reviews of GALILEO\u27S ...
Merz, Jon F.
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

ALight [PDF]

open access: yes, 2012
Between 2007-2012 AIR worked with Islington Council Arts Team and the Archway Town Centre Management Group to commission new works that explored a perceived darkness in Archway.
Hart, Anna
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The sorting protein GASP-1 regulates the constitutive signaling capacity of the virally encoded chemokine receptor US28 [PDF]

open access: hybrid, 2009
Pia Tschische   +9 more
openalex   +1 more source

The Future for Iraq: Realities and Requirements [PDF]

open access: yes, 2006
According to Zinni, the American people sent a clear message on Nov. 7 that they will no longer accept the current course in Iraq. With few good policy options left, the former head of Central Command suggests that we look at what might still work ...
Anthony Zinni
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy