Results 161 to 170 of about 746,055 (241)

Phase IIB, Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial of Intravenous Defibrotide for the Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome in COVID‐19

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Introduction Endothelial dysfunction is key in COVID‐19 pathogenesis. This randomized, double‐blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS‐CoV‐2 infection and respiratory failure.
Ruben Jara Rubio   +38 more
wiley   +1 more source

House Dust Mite Sensitisation Effectively Differentiates Atopy From Non‐Atopy in the Tropical Environment of Southeast Asia

open access: yes
Clinical &Experimental Allergy, EarlyView.
Yang Yie Sio   +4 more
wiley   +1 more source

Third Allogeneic Stem Cell Transplantation in Children: A Multicenter Analysis From the Spanish GETH‐TC Pediatric Group

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Third allogeneic hematopoietic stem cell transplantation (HSCT3) is rarely performed in pediatric patients and is associated with high toxicity and mortality. Data on outcomes in this setting remain scarce. We conducted a retrospective multicenter study within the Spanish GETH‐TC Pediatric group including 29 children and adolescents who ...
Luisa Sisinni   +17 more
wiley   +1 more source

The Challenges of Backsourcing

open access: yesFinancial Accountability &Management, EarlyView.
ABSTRACT Public sector outsourcing sometimes ends in unexpected termination, forcing authorities to engage in backsourcing. The aim of this study is to identify the challenges posed by unexpected terminations of sourcing contracts in the public sector and analyze how actual practices in these situations diverge from theoretical expectations in the ...
Johan Berlin   +3 more
wiley   +1 more source

The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes

open access: yesThe FEBS Journal, EarlyView.
Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova   +12 more
wiley   +1 more source

The Impact of Assessing Patients' Sense of Security on Nurses' Intent to Report Safety Events: A Factorial Survey Experiment

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aims To evaluate whether information about patients' poor sense of security in hypothetical vignette scenarios increases nurses' projected intent to report safety events. Design Quantitative, cross‐sectional factorial survey vignette experiment administered online.
Patricia S. Groves   +3 more
wiley   +1 more source

The Epistemic Harms of Botched Apologies for Past Wrongs

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT Apologies often create expectations of meaningful change and repair. Yet when institutions or states deliver apologies for past wrongs that lack substantive reparative action, they risk deepening, rather than redressing, the harms they acknowledge.
Abraham Tobi
wiley   +1 more source

Tree growth response and adaptation to climate change and climate extremes: From canopy to stem

open access: yesJournal of Integrative Plant Biology, EarlyView.
This review synthesizes the responses and adaptations of tree growth, including canopy phenology, intra‐annual wood formation dynamics, and annual stem growth, to climate change and climate extremes. It highlights key knowledge gaps for future research to support sustainable forest management and enhance forest carbon storage under ongoing climate ...
Feiyu Yang   +8 more
wiley   +1 more source

Decoding stress resilience in soybean: Regulatory networks and precision breeding under climate change

open access: yesJournal of Integrative Plant Biology, EarlyView.
This review covers recent progress in the understanding of stress‐responsive regulatory networks in soybean and highlights emerging genomic and breeding strategies. Integrating molecular insights and precision breeding will help to accelerate the development of climate‐resilient soybean cultivars.
Ali Shahzad   +8 more
wiley   +1 more source

Anatomy of spinal CSF loss in the American alligator (Alligator mississippiensis)

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 575-584, April 2025.
India ink introduced into the cranial cerebrospinal fluid (CSF) compartment of Alligator diffuses along the spinal cord and exits the spinal compartment using perineural flow, resulting in a prominent “ink cuff” forming at the base of the spinal nerve. In Alligator, the region of the ink cuff is drained by a small lymphatic vessel.
Hadyn DeLeeuw   +5 more
wiley   +1 more source

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