Results 1 to 10 of about 6,864 (176)

Genetic evidence for inhibition of bacterial division protein FtsZ by berberine. [PDF]

PLoS ONE, 2010
BACKGROUND: Berberine is a plant alkaloid that is widely used as an anti-infective in traditional medicine. Escherichia coli exposed to berberine form filaments, suggesting an antibacterial mechanism that involves inhibition of cell division.
Jaroslaw M Boberek, Jem Stach, Liam Good
doaj   +1 more source

Time-Series Chlorophyll Fluorescence Imaging Reveals Dynamic Photosynthetic Fingerprints of sos Mutants to Drought Stress

Sensors, 2019
Resistance to drought stress is one of the most favorable traits in breeding programs yet drought stress is one of the most poorly addressed biological processes for both phenomics and genetics.
Dawei Sun, Yueming Zhu, Haixia Xu, Yong He, Haiyan Cen   +4 more
doaj   +1 more source

An Inquiry-Based Laboratory Module to Promote Understanding of the Scientific Method and Bacterial Conjugation

Journal of Microbiology & Biology Education, 2014
Students are engaged and improve their critical thinking skills in laboratory courses when they have the opportunity to design and conduct inquiry-based experiments that generate novel results.
Melanie B. Berkmen, Anastasia C. Murthy, Matthew P. Broulidakis   +2 more
doaj   +1 more source

Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice

Hepatology, EarlyView., 2022
Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim, Jaewoong Lee, Hyun Joo Shin, Eun Ae Jeong, Hye Min Jang, Yu Jeong Ahn, Hyeong Seok An, Jong Youl Lee, Meong Cheol Shin, Soo Kyoung Kim, Won Gi Yoo, Won Ho Kim, Gu Seob Roh   +12 more
wiley   +1 more source

Signal Enhancement by a Multi-layered Substrate for Mutagen Detection Using an SOS Response-induced Green Fluorescent Protein in Genetically Modified Escherichia coli

Analytical Sciences, 2011
In this paper, we describe a method to enhance the fluorescence signal of mutagen detection using SOS response-induced green fluorescence protein (GFP) in genetically modified Escherichia coli using a multi-layered substrate. To generate E. coli that express SOS response-induced GFP, we constructed a plasmid carrying the RecA promoter located upstream
ETOH, Hiroki, YASUDA, Mitsuru, AKIMOTO, Takuo   +2 more
openaire   +3 more sources

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Flexible Pressure Sensor With Co‐Optimized Sensitivity and Linearity Based on Gradient Toroidal Microstructures

Advanced Materials Technologies, EarlyView.
A flexible piezoresistive pressure sensor with gradient toroidal CNT/PDMS microstructures is reported. The hierarchical geometry enables sequential electrode contact, achieving a sensitivity of 256.20 kPa−1 and linear response (R2 = 0.99) over 0–1000 kPa.
Rongmei Wang, Ruolin Liu, Ming Lei, Yifan Liu, Fengming Hu, Bing Ji, Chao Peng, Jianyi Luo, Bingpu Zhou   +8 more
wiley   +1 more source

Multiobjective Codesign Optimization of a Planar Pneumatic Artificial Muscle‐Based Snake‐Like Robot for Enhanced Agility and Energy Efficiency

Advanced Robotics Research, EarlyView.
A codesign multiobjective optimization framework was developed to enhance the morphology and controller of a snake‐like robot driven by artificial muscles. It improved planar locomotion, agility, and power efficiency. The approach optimized link geometry and controller gains, revealing that shorter muscles near joints and longer linkages maximize ...
Ayla Valles, Mahdi Haghshenas‐Jaryani
wiley   +1 more source

Empowering and conquering infirmity of visually impaired using AI‐technology equipped with object detection and real‐time voice feedback system in healthcare application

CAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract The Internet of Things is emerging as a crucial technology in aiding humans and making their lives easier. Among the human population, a large percentage of people suffer from disabilities resulting in challenges in everyday life particularly people with visual disabilities.
Hania Tarik, Shahzad Hassan, Rizwan Ali Naqvi, Saddaf Rubab, Usman Tariq, Monia Hamdi, Hela Elmannai, Ye Jin Kim, Jae‐Hyuk Cha   +8 more
wiley   +1 more source