Results 91 to 100 of about 6,971 (209)
The WHO Classification of Genetic Tumour Syndromes: Considerations for Genetics
Clinical Genetics, EarlyView.The WHO Classification of Tumours underpins the diagnosis of neoplastic conditions. The new WHO classification of genetic tumour syndromes (GTS) provides international standards for their diagnosis. This diagram highlights the chromosomal distribution of the genes involved in the GTS covered in this classification.
Ian A. Cree +18 more
wiley +1 more source
Effect of subinhibitory concentrations of ciprofloxacin on Mycobacterium fortuitum mutation rates
, 2005 Objectives: Fluoroquinolones have found a place in the management of mycobacterial diseases including tuberculosis. It has been previously shown that subinhibitory concentrations of quinolones increase the mutation rate in Escherichia coli and ...
Basu, Shreya +13 more
core +1 more source
Building Trust in the First Stages of Research With Children
Children &Society, EarlyView.ABSTRACT This article focuses on the process of building trust in the first stages of research with children. Based on three research examples conducted in Finland, we analyse the ways of building trust and illustrate how trust or distrust can emerge in research with children.
Terhi Tuukkanen, Elina Weckström
wiley +1 more source
, 1995 International audienceIn a previous paper, we reported that the reactivity level, which regulates the frequency of transposition of I factor, a LINE element-like retrotransposon, is enhanced by the same agents that induce the SOS response in Escherichia ...
Bregliano, Jean-Claude, Laurençon, Anne
core +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Introduction Endothelial dysfunction is key in COVID‐19 pathogenesis. This randomized, double‐blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS‐CoV‐2 infection and respiratory failure.
Ruben Jara Rubio +38 more
wiley +1 more source
Objective: This study investigates the oxidative stress mechanisms induced by ciprofloxacin in Staphylococcus aureus, focusing on reactive oxygen species (ROS) generation, antioxidant responses, and cellular damage.
Yaqoob Rahi, Alaa
core +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Third allogeneic hematopoietic stem cell transplantation (HSCT3) is rarely performed in pediatric patients and is associated with high toxicity and mortality. Data on outcomes in this setting remain scarce. We conducted a retrospective multicenter study within the Spanish GETH‐TC Pediatric group including 29 children and adolescents who ...
Luisa Sisinni +17 more
wiley +1 more source
The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes
The FEBS Journal, EarlyView.Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova +12 more
wiley +1 more source
Childbearing patterns for Swedish mothers of twins, 1961-1999 [PDF]
The Nordic population registers provide a unique possibility to study the demographic behavior of very small population groups and rare events. In this paper, we study the childbearing behavior of Swedish mothers of twins between 1961 and 1999, inclusive.
Margit Strandberg, Jan M. Hoem
core
The Epistemic Harms of Botched Apologies for Past Wrongs
Journal of Applied Philosophy, EarlyView.ABSTRACT Apologies often create expectations of meaningful change and repair. Yet when institutions or states deliver apologies for past wrongs that lack substantive reparative action, they risk deepening, rather than redressing, the harms they acknowledge.
Abraham Tobi
wiley +1 more source