Results 101 to 110 of about 72,292 (263)
A swarm intelligence framework for reconstructing gene networks: searching for biologically plausible architectures [PDF]
Kentzoglanakis, Kyriakos, Poole, Matthew
core +1 more source
Cardiotoxicity of BRAF/MEK inhibitors
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe +4 more
wiley +1 more source
ABSTRACT This article presents a methodological study examining how inclusive, visually supported workshops can facilitate the participation of children with disabilities in research on family life. The study demonstrates how the combined use of visual structuring, sensory‐aware pacing and relational scaffolding can expand communicative possibilities ...
Cecilie K. Moesby‐Jensen +1 more
wiley +1 more source
ABSTRACT Young people transitioning from out‐of‐home care, also known as care leavers, are globally recognised as a vulnerable group. There is a scarcity of literature on leaving care across the Global South, including Asia. The authors examined policies and practices from the grey literature to gain insights from broader literature beyond peer ...
Rangga Radityaputra +2 more
wiley +1 more source
Building Trust in the First Stages of Research With Children
ABSTRACT This article focuses on the process of building trust in the first stages of research with children. Based on three research examples conducted in Finland, we analyse the ways of building trust and illustrate how trust or distrust can emerge in research with children.
Terhi Tuukkanen, Elina Weckström
wiley +1 more source
ABSTRACT Acute lymphoblastic leukaemia (ALL) in older adults represents a growing clinical challenge, driven by an ageing population, adverse disease biology, and reduced tolerance to intensive chemotherapy. Although pediatric‐inspired regimens have improved outcomes in younger adults with Philadelphia chromosome (Ph)‐negative ALL, survival in older ...
Antonella Bruzzese +12 more
wiley +1 more source
Exploring plant tolerance to biotic and abiotic stresses [PDF]
Plants are exposed to many stress factors, such as drought, high salinity or pathogens, which reduce the yield of the cultivated plants or affect the quality of the harvested products. Arabidopsis thaliana was used as a model plant to study the responses
Karim, Sazzad
core
Targeting the Menin–KMT2A Axis in Acute Leukemia: From Epigenetic Dependency to Clinical Translation
ABSTRACT Acute leukemias characterized by a shared epigenetic dependency on the menin–KMT2A axis rely on aberrant HOX‐driven transcriptional programs that sustain leukemic self‐renewal and impair differentiation. This dependency is most evident in KMT2A‐rearranged and NPM1‐mutated acute myeloid leukemia (AML), but also extends to other HOX‐dependent ...
Antonella Bruzzese +12 more
wiley +1 more source

