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SOS response as an adaptive response to DNA damage in prokaryotes [PDF]
Escherichia coli possesses an elaborate adaptive mechanism called the "SOS response" to cope with various types of DNA damage. More than 20 SOS genes, most of which are known to be involved in the functions that promote the survival of DNA-damaged cells, are induced by treatments that damage DNA or inhibit DNA synthesis. All the SOS genes share similar
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Tanning as Part of the Eukaryotic SOS Response
Pigment Cell Research, 2000We have determined that DNA damage is at least one of the signals generated by ultraviolet radiation that stimulates pigmentation (tanning) in human skin. This photoprotective response is functionally similar to the SOS response described in bacteria.
Barbara A. Gilchrest, Mark S. Eller
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Responsivity of Gated Photodiode in SOS Technology
2007 IEEE Sensors, 2007We report on the responsivity of silicon-on-sapphire (SOS) gated photodiode. A test chip, consisting of 1024 photodetectors, connected in parallel, was fabricated in a Peregrine's 0.5 mum SOS technology and successfully tested by direct photocurrent measurements.
E. Culurciello+2 more
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Modulation of the SOS response by truncated RecA proteins
Molecular and General Genetics MGG, 1989RecA protein plays several key roles in the SOS response. We have constructed truncated proteins and examined their capacity to accomplish Weigle reactivation and mutagenesis of bacteriophage lambda and recombination in Escherichia coli. Our data indicate that the 17 carboxyl terminal amino acids are not essential to RecA function.
M. Defais, Florence Larminat
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Not So Fast! A Response to Michael Guilfoyle
Journal of Constructivist Psychology, 2015Although finding many places of agreement with Michael Guilfoyle's argument, I am also disappointed with his central conclusions. There are indeed nondiscursive lines of force, but these do not necessarily contradict the logic of discursive positioning.
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Dopa-Responsive Dystonia - The Story so Far
Neuropediatrics, 2002Dopa-responsive dystonia (DRD) is an eminently treatable condition and its recognition is therefore of crucial importance. In classical cases, the disease manifests in early childhood with walking problems due to dystonia of the lower limbs. The dystonia is frequently accompanied by "parkinsonian" features such as reduced facial expression or slowing ...
Oliver Bandmann, Nicholas W. Wood
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Induction of the SOS response by new 4-quinolones
Journal of Antimicrobial Chemotherapy, 1987The 4-quinolones ciprofloxacin, difloxacin, enoxacin, norfloxacin, ofloxacin, and nalidixic acid were found to induce the SOS response in qualitative and quantitative tests on Escherichia coli K12 containing the sfiA::lacZ gene fusion. Maximum induction of the SOS-response was observed with the quinolone concentrations that produced the most killing ...
Felipe Moreno+3 more
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How basic is palliative care? A response to the responses so far
International Journal of Palliative Nursing, 2005Continuing the debate on the nature of palliative care (Gupta, 2004; Downing et al, 2005), Harmala Gupta comes back with her thoughts on the issues raised so far.
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So What Next? A Policy Response
2018There are more UK-national black and minority ethnic (BME) staff working in higher education now than there were eight years ago. However while there has been a slight increase in the percentage of BME UK-national academics working in the sector, at the professoriate level, there are only 60 Black professors in the UK.
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RecA protein in the SOS response: milestones and mysteries
Biochimie, 1991The role of RecA protein in the SOS response of Escherichia coli is traced from the isolation of the first recA mutant to our current understanding of the scope and regulation of this DNA damage-inducible system. In addition, possible RecA protein activities that may be essential in the expression of several SOS phenotypes (stable DNA replication, DNA ...
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