Results 201 to 210 of about 2,634,872 (277)

Bioengineered Stroma‐Camouflaged Nanovesicles Disrupt the IDO1/CD276 Immunosuppressive Circuit to Reinvigorate Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
Bioengineered stroma‐camouflaged nanovesicles (AM@UIO‐BMS/DOX) convert the immunosuppressive tumor niche into an immunoresponsive milieu by disrupting the IDO1/CD276 circuit. Anti‐CD276 membrane camouflage guides tumor accumulation and deep penetration, enabling controlled co‐delivery of DOX and the IDO1 inhibitor BMS‐986205.
Ziqi Zhang   +11 more
wiley   +1 more source

LLM‐Assisted Design of Ultralow‐κ$\kappa$ Chalcogenides

open access: yesAdvanced Science, EarlyView.
An AI assisted, physics guided workflow accelerates the discovery of ultralow thermal conductivity materials by combining Bayesian optimization, evidence conditioned LLM reasoning, and automated physics‐based validation. The framework uncovers dynamically stable Ag based chalcogenides with ultralow thermal conductivity and promising thermoelectric ...
Yujie Liu   +9 more
wiley   +1 more source

Sensitivity of helioseismic measurements of normal-mode coupling to flows and sound-speed perturbations. [PDF]

open access: yesMon Not R Astron Soc, 2017
Hanasoge SM   +4 more
europepmc   +1 more source

Targeted Mechanogenetics to Modulate Specific Deep Neural Circuits

open access: yesAdvanced Science, EarlyView.
This study introduces mechanogenetics, a nanobubble‐enhanced sonogenetic strategy for selective modulation of feeding‐related neural circuits in the mouse lateral hypothalamus. Mechanogenetic stimulation modulates feeding behavior through glutamatergic projections from the lateral hypothalamus to the ventral tegmental area, highlighting its potential ...
Xuandi Hou   +3 more
wiley   +1 more source

Spatiotemporal Regulation of Hierarchical Assembly of Hydroxyapatite for Enamel Remineralization

open access: yesAdvanced Science, EarlyView.
Biomimetic repair exhibits unique advantages for enamel regeneration compared with conventional clinical treatments. An enzymatic mineralization system (EMS) is developed, where the resulting HAP nanorods hierarchically assemble into a highly ordered structure on the enamel surface through the spatiotemporal modulation of interfacial energies of ...
Zhenhang Tang   +15 more
wiley   +1 more source

Optical Access to Dark Excitons Via Spin–Phonon Fano Interference

open access: yesAdvanced Science, EarlyView.
Dark excitons in quantum dots neither absorb nor emit light and stay hidden from optical spectroscopy. Quantum interference now reveals them: light scattered by acoustic phonons interferes with a phonon‐assisted spin flip between bright and dark exciton, carving a Fano dip into the spectrum whose position gives the bright–dark splitting. Magnetic field,
Janina J. Schindler   +7 more
wiley   +1 more source

A Compact and Fast Single‐Spike TTFS Encoder With Ultralow Operating Voltage for Efficient Neuromorphic Fourier Transform

open access: yesAdvanced Science, EarlyView.
A Pt/TaOx/V single‐spike TTFS encoder achieves ultralow‐voltage (∼0.35 V), high‐speed (∼100 ns) operation with simplified circuitry. Integrating bipolar nonuniform temporal encoding with a spiking‐DFT neuron model enables a neuromorphic FFT framework. Device‐calibrated simulations demonstrate high spectral fidelity across multitone, speech, and chirp ...
Yang Wu   +10 more
wiley   +1 more source

Hybrid Spring‐Coupled Broadband Energy Harvester Integrated with CuSCN Functionalized Triboelectric Vibration Sensor for Self‐Sustainable Vehicular IoTs

open access: yesAdvanced Science, EarlyView.
A self‐sustainable vehicular vibration and indoor environment monitoring IoT platform is developed which integrates a hybrid spring‐coupled broadband energy harvester with a machine learning‐assisted PAN‐CuSCN nanofiber triboelectric vibration sensor for subtle‐to‐wide‐range vibration detection and road/speed classification.
Trilochan Bhatta   +6 more
wiley   +1 more source

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