Results 1 to 10 of about 669,768 (234)

Anaerobic Bioremediation of Groundwater Containing High Concentrations of cis-1,2-Dichloroethene Using Solid Amendments

open access: yesRevista Águas Subterrâneas, 2013
A ruptured degreaser introduced trichloroethylene (TCE) into groundwater at an industrial facility in Stephenville, TX. Groundwater near the source zone (30m by 15m) had TCE concentrations near 500 mg/L, suggesting that un-dissolved contaminant was ...
John Freim   +4 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Recombinant Live-Attenuated Salmonella Vaccine for Veterinary Use

open access: yesVaccines
Vaccination is essential for maintaining animal health, with priority placed on safety and cost effectiveness in veterinary use. The development of recombinant live-attenuated Salmonella vaccines (RASVs) has enabled the construction of balanced lethal ...
Domitila Brzoskowski Chagas   +4 more
doaj   +1 more source

Attenuation From Shoes and Pads in Equine Nuclear Scintigraphy, With Relevance to Solar Views

open access: yesFrontiers in Veterinary Science, 2020
Nuclear scintigraphy can be beneficial in the investigation of equine lameness and poor performance. Images obtained through the sole allow for better identification of a region of increased radionuclide uptake in the foot.
Lea Walker   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Application of Ultrasonic Lamb Wave Logging Technology in Bohai Oilfield

open access: yesShiyou jixie, 2020
It is restricted and difficult for present sonic logging and sector cement logging technologies used in cementing quality evaluation of low-density cement slurry, casing eccentricity evaluation and casing damage detection. An ultrasonic Lamb wave logging
Han Yaotu   +4 more
doaj  

Influence of Selected Parameters on Eddy Currents Attenuation in Non-Destructive Inspection

open access: yesCommunications, 2013
Eddy currents attenuation in conductive materials under non-destructive inspection is analyzed in the paper. Influence of selected parameters of the inspection on the attenuation is studied by numerical means.
Ladislav Janousek
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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