Results 111 to 120 of about 17,122,186 (353)
Evolution of solar wind sources and coronal rotation driven by the cyclic variation of the Sun's large-scale magnetic field [PDF]
, 2023 Adam J. Finley, A. S. Brun
openalex +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Sahabe Tefsirinin Bilgi ve Kaynak Değeri
Darulhadis İslami Araştırmalar Dergisi, 2022 Sahabe, Müslümanların nezdinde, çok değerli bir yere sahiptirler. Zira Hz. Peygamber (s.a.v.)’e sadakatle bağlanmaları ve canları ve malları ile onun yanında durarak destek olmaları bu duyuşsal algıyı oluşturan en önemli sebeplerden biridir.
Reşit Özer
doaj
Evidence for recombination as a significant source of metastable helium [PDF]
, 1998 J. Noto +9 more
openalex +1 more source
Control for nuclear thermionic power source [PDF]
, 1978 A control for a power source which includes nuclear fuel interspersed with thermionic converters, is described. A power regulator maintains a substantially constant output voltage to a variable load, and a control circuit drives a neutron flux regulator ...
Sawyer, C. D.
core +1 more source
Intense Source of Slow Positrons
, 2004 We describe a novel design for an intense source of slow positrons based on pair production with a beam of electrons from a 10 MeV accelerator hitting a thin target at a low incidence angle.
A. Rosowsky +17 more
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Why Modern Open Source Projects Fail
, 2017 Open source is experiencing a renaissance period, due to the appearance of modern platforms and workflows for developing and maintaining public code. As a result, developers are creating open source software at speeds never seen before.
Androutsellis-Theotokis Stephanos +5 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source