Results 91 to 100 of about 6,630,130 (315)

Fake source-based source location privacy in wireless sensor networks [PDF]

open access: yes, 2015
The development of novel wireless sensor network (WSN) applications, such as asset monitoring, has led to novel reliability requirements. One such property is source location privacy (SLP).
Bradbury, Matthew S.   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

ATEİZM VE ÇEŞİTLERİ

open access: yesFelsefe Dünyası, 2007
Murtaza KORLAELÇİ, "ATEİZM VE ÇEŞİTLERİ", FELSEFE DÜNYASI DERGİSİ, SAYI ...
Murtaza Korlaelçi
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

FLOSS tools in computer forensics tertiary education

open access: yes, 2008
In this paper we discuss the application of Free, Libre, and Open Source Software (FLOSS) tools in computer forensics education at tertiary level. We argue that FLOSS tools are more suitable than commercial tools, as they provide the opportunity for ...
Bem, Derek   +2 more
core  

Sahabe Tefsirinin Bilgi ve Kaynak Değeri

open access: yesDarulhadis İslami Araştırmalar Dergisi, 2022
Sahabe, Müslümanların nezdinde, çok değerli bir yere sahiptirler. Zira Hz. Peygamber (s.a.v.)’e sadakatle bağlanmaları ve canları ve malları ile onun yanında durarak destek olmaları bu duyuşsal algıyı oluşturan en önemli sebeplerden biridir.
Reşit Özer
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy