Results 111 to 120 of about 6,630,130 (315)
Role of Quality Source Code Documentation in Software Testing
, 2014 Software testing is performed to validate that software under test meets all requirements. With the increase in software developing platforms, developers may commit those errors, which, if not tested with appropriate test cases, may lead to false ...
Kalia, Arvind +2 more
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Open source software and the library community
, 2000 This paper examines whether the library community should support the development of open source software, software whose licensing allows its source code, the part of a computer program that is readable by humans, to be redistributed and/or modified ...
Clarke, Kevin S., Clarke, Kevin
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Amplify your research and mobilize your knowledge with SOURCE
Library and Learning Services Are you seeking new avenues to amplify the reach of your scholarly and creative works and to reach new audiences? Explore how SOURCE: Sheridan’s institutional repository not only preserves your research but also enhances ...
Duguay, Adam
core
, 1993 "June, 1993."1) Bibliography of Citizen's Volunteer Monitoring References --2) Children's Water Conservation Fact Sheet -- 3) Citizen's Volunteer Monitoring Program Technical Assistants -- 4) Ecological Indicators -- 5) Freshwater Mussels in Kansas -- 6)
Kansas. Nonpoint Source Section.
core
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source