Results 91 to 100 of about 11,579,038 (330)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

On the Effect of Semantically Enriched Context Models on Software Modularization

open access: yes, 2017
Many of the existing approaches for program comprehension rely on the linguistic information found in source code, such as identifier names and comments.
Hage, Jurriaan   +3 more
core   +2 more sources

VSEARCH: a versatile open source tool for metagenomics

open access: yesPeerJ, 2016
Background VSEARCH is an open source and free of charge multithreaded 64-bit tool for processing and preparing metagenomics, genomics and population genomics nucleotide sequence data.
Torbjørn Rognes   +4 more
semanticscholar   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

Employing Blockchain, NFTs, and Digital Certificates for Unparalleled Authenticity and Data Protection in Source Code: A Systematic Review

open access: yesComputers
In higher education, especially in programming-intensive fields like computer science, safeguarding students’ source code is crucial to prevent theft that could impact learning and future careers.
Leonardo Juan Ramirez Lopez   +1 more
doaj   +1 more source

On source and channel codes for multiple inputs and outputs: does multiple description beat space time? [PDF]

open access: yes, 2005
We compare two strategies for lossy source description across a pair of unreliable channels. In the first strategy, we use a broadcast channel code to achieve a different rate for each possible channel realization, and then use a multiresolution source ...
Effros, Michelle   +3 more
core  

Automatic Generation of Text Descriptive Comments for Code Blocks

open access: yes, 2018
We propose a framework to automatically generate descriptive comments for source code blocks. While this problem has been studied by many researchers previously, their methods are mostly based on fixed template and achieves poor results.
Liang, Yuding, Zhu, Kenny Q.
core   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Consider the Source: The Value of Source Code to Digital Preservation Strategies [PDF]

open access: yes, 2013
One of the major challenges in the digital preservation field is the difficulty of ensuring long-term access to digital objects, especially in cases when the software that was used to create an object is no longer current.
Castagné, Michel
core   +1 more source

GYRE: A New Open-Source Stellar Oscillation Code

open access: yes, 2013
We introduce GYRE, a new open-source stellar oscillation code which solves the adiabatic/non-adiabatic pulsation equations using a novel Magnus Multiple Shooting (MMS) numerical scheme.
Paxton, Bill   +2 more
core   +1 more source

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