Results 41 to 50 of about 729,783 (267)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Gaussian source coding with spherical codes [PDF]

IEEE Transactions on Information Theory, 2002
Summary: A fixed-rate shape-gain quantizer for the memoryless Gaussian source is proposed. The shape quantizer is constructed from wrapped spherical codes that map a sphere packing in \(\mathbb R^{k-1}\) onto a sphere in \(\mathbb R^k\), and the gain codebook is a globally optimal scalar quantizer.
Jon Hamkins, Kenneth Zeger
openaire   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Automated Authorship Identification of Program Code Based on a Metric System

Information Technologies and Systems
 The paper reviews existing methods for automated program code authorship attribution and then proposes an original method based on a system of metrics. The proposed method uses a metric system grounded in the “fingerprinting” technique.
A.H. Adamchuk, V.I. Sushchuk-Slusarenko, A.I. Dychka   +2 more
doaj   +1 more source

Integer-Forcing Source Coding [PDF]

IEEE Transactions on Information Theory, 2014
Integer-Forcing (IF) is a new framework, based on compute-and-forward, for decoding multiple integer linear combinations from the output of a Gaussian multiple-input multiple-output channel. This work applies the IF approach to arrive at a new low-complexity scheme, IF source coding, for distributed lossy compression of correlated Gaussian sources ...
Or Ordentlich, Uri Erez
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Integrated Technique of Natural Language Texts and Source Codes Authorship Verification in the Academic Environment

IEEE Access
The issue of text plagiarism in academic and educational environments is becoming increasingly relevant every year. The quality of research articles and works is declining due to students copying fragments of others’ works and using modern ...
Aleksandr Romanov, Anna Kurtukova, Anastasiia Fedotova, Alexander Shelupanov   +3 more
doaj   +1 more source

L’écriture collective du code source informatique

Revue d'anthropologie des connaissances, 2012
This article analyzes the collective writing of software source code. Software source code is a set of textual documents that formally specify the behavior of software – its script. The article draws on work in the sociology of science and technology and
Stéphane Couture
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source