Results 111 to 120 of about 16,051,352 (293)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The role of dental assessment in source identification during Staphylococcus aureus bacteremia: a scoping review

Frontiers in Oral Health
ObjectivesStaphylococcus aureus bacteremia (SAB) is a severe bloodstream infection associated with substantial morbidity, mortality, and metastatic complications.
Laura Isabell Werneburg, Jeremias Hey, Karl-Stefan Delank, Felix Werneburg   +3 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Open source software and libraries [PDF]

, 2008
Open source software is, software that users have the ability to run, copy, distribute, study, change, share and improve for any purpose. Open source library software’s does not need the initial cost of commercial software and enables libraries to have ...
Randhawa, Sukhwinder
core   +1 more source

Reassessing Antibiotic Duration in Dental Infections: A Narrative Review and Marginal Benefit–Harm Framework with a Clinical Checklist

Antibiotics
Antibiotic duration is a central question in antimicrobial stewardship, yet dental prescribing often remains anchored to fixed five- or seven-day courses despite the source-control-dependent nature of many odontogenic infections.
Jelena Roganović, Vuk Roganović
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

The Feasibility of Short-Course Antibiotic Therapy and Source Control for Elderly Patients With Gram-Negative Bacteremic Biliary Tract Infection: A Retrospective Cohort Study

Journal of Hospital General Medicine
Background and Aims: The optimal duration of antibiotic therapy for elderly patients with gram-negative bacteremic biliary tract infection (BTI) remains unclear.
Kenya Toma, Yasuharu Tokuda
doaj   +1 more source

Modern sources of controls in case-control studies

American Journal of Epidemiology
Abstract In 1992, Wacholder et al. developed a theoretical framework for case-control studies to minimize bias in control selection. They described 3 comparability principles (study base, deconfounding, and comparable accuracy) to reduce the potential for selection bias, confounding, and information bias in case-control studies ...
Hailey R Banack, Matthew P Fox, Robert W Platt, Michael D Garber, Xiaojuan Li, Jonathan Schildcrout, Ellicott C Matthay   +6 more
openaire   +4 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Estimation and control for an open-source quadcopter [PDF]

, 2011
This paper describes modelling, estimation and control of the horizontal translational motion of an open-source and cost effective quadcopter — the MikroKopter.
Sa, Inkyu, Corke, Peter
core