Results 51 to 60 of about 11,908,024 (286)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Mathematics, 2022 Large-scale inverse problems that require high-performance computing arise in various fields, including regional air quality studies. The paper focuses on parallel solutions of an emission source identification problem for a 2D advection–diffusion ...
Alexey Penenko, Evgeny Rusin
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Numerical solutions of source identification problems for telegraph-parabolic equations
Қарағанды университетінің хабаршысы. Математика сериясыThis paper presents a numerical study of source identification problems for one-dimensional telegraphparabolic equations subject to Dirichlet and Neumann boundary conditions.
M. Ashyraliyev, M.A. Ashyralyyeva
doaj +1 more source
Lagrangian relaxation heuristics for the uncapacitated single-source multi-product facility location problem [PDF]
, 2013 Facility location problem is one of the strategic logistical drivers within the supply chain which is a hard to solve optimization problem. In this study, we focus on the uncapacitated single-source multi-product production/distribution facility location
Nezhad, Ali Mohammad +2 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Қарағанды университетінің хабаршысы. Математика сериясыThe space-dependent source identification problem for the two-dimensional neutron transport equation with spatially variable coefficients and periodic boundary conditions is investigated. The neutron transport equation is a fundamental model for neutron
A. Ashyralyev, A. Taskin
doaj +1 more source
On determination of the source term of a modified KdV equation
Hittite Journal of Science and Engineering, 2018 We study an inverse problem to identify the source term depending on x of a modified KdV equation. In order to recover source term, we define an inverse problem subject to an overdetermination condition.
Müjdat Kaya
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Heating source localization in a reduced time
International Journal of Applied Mathematics and Computer Science, 2016 Inverse three-dimensional heat conduction problems devoted to heating source localization are ill posed. Identification can be performed using an iterative regularization method based on the conjugate gradient algorithm.
Beddiaf Sara +3 more
doaj +1 more source