Results 61 to 70 of about 11,908,024 (286)

Importance of the class of harmonic sources in the identification of sources in the inverse electroencephalographic problem

Nova Scientia, 2020
Introduction: In this work we discuss the relevance of the harmonic sources on the brain volume, which reproduce a given potential distribution on the scalp. These sources, apart from being a unicity class, they play a fundamental role in the resolution of the inverse problem of source identification with respect to any other sources class.Method: We ...
Javier Mozqueda Lafarga, Andrés Fraguela Collar, Moisés Soto Bajo, Javier Herrera Vega   +3 more
openaire   +3 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Identification of source term for the ill-posed Rayleigh–Stokes problem by Tikhonov regularization method

Advances in Difference Equations, 2019
In this paper, we study an inverse source problem for the Rayleigh–Stokes problem for a generalized second-grade fluid with a fractional derivative model. The problem is severely ill-posed in the sense of Hadamard. To regularize the unstable solution, we
Tran Thanh Binh, Hemant Kumar Nashine, Le Dinh Long, Nguyen Hoang Luc, Can Nguyen   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Investigation of a Time-Dependent Source Identification Inverse Problem with Integral Overdetermination

, 2020
In the present paper, a time-dependent source identification problem subject to an integral overdetermination is considered. Stability estimates for this differential problem are established. Furthermore, a first and a second order of accuracy difference
Ashyralyev A., Sazaklioglu A.U.
core   +2 more sources

Utilization of a Bayesian probabilistic inferential framework for contamination source identification in river environment

MATEC Web of Conferences, 2018
In the environmental event of hazardous release into river, quick and accurate identification of the contamination source is important for emergence response. Generally, given a noisy and finite set of monitoring information, determining the source items
Jing Lijun, Chen Ruihui, Bai Xiaomei, Meng Fansheng, Yao Zhipeng, Teng Yanguo, Chen Haiyang   +6 more
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Identification of Product Innovation Opportunity Based on Problem and Suggestions Using Dual-Source Data [PDF]

Nongye tushu qingbao xuebao
[Purpose/Significance] As the user base grows, the number of online comments is increasing rapidly. The massive volume of comments has broadened the innovative thinking of enterprises and provided more diverse innovative options, but it has also brought ...
GUO Yanli, GAO Rui, ZOU Meifeng, LIU Zidan
doaj   +1 more source