Results 61 to 70 of about 2,201,987 (292)

Heating source localization in a reduced time

International Journal of Applied Mathematics and Computer Science, 2016
Inverse three-dimensional heat conduction problems devoted to heating source localization are ill posed. Identification can be performed using an iterative regularization method based on the conjugate gradient algorithm.
Beddiaf Sara, Autrique Laurent, Perez Laetitia, Jolly Jean-Claude   +3 more
doaj   +1 more source

An L∞ regularisation strategy to the inverse source identification problem for elliptic equations [PDF]

, 2019
In this paper we utilise new methods of Calculus of Variations in L ∞ to provide a regularisation strategy to the ill-posed inverse problem of identifying the source of a non-homogeneous linear elliptic equation, satisfying Dirichlet data on a domain ...
Bocea M., Nikos Katzourakis, Shigeta T., Xie O.   +3 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Identifying hedonic models [PDF]

, 2001
Economic models for hedonic markets characterize the pricing of bundles of attributes and the demand and supply of these attributes under different assumptions about market structure, preferences and technology.
Ekeland, I., Heckman, J., Nesheim, L.
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Identification of source term for the ill-posed Rayleigh–Stokes problem by Tikhonov regularization method

Advances in Difference Equations, 2019
In this paper, we study an inverse source problem for the Rayleigh–Stokes problem for a generalized second-grade fluid with a fractional derivative model. The problem is severely ill-posed in the sense of Hadamard. To regularize the unstable solution, we
Tran Thanh Binh, Hemant Kumar Nashine, Le Dinh Long, Nguyen Hoang Luc, Can Nguyen   +4 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Utilization of a Bayesian probabilistic inferential framework for contamination source identification in river environment

MATEC Web of Conferences, 2018
In the environmental event of hazardous release into river, quick and accurate identification of the contamination source is important for emergence response. Generally, given a noisy and finite set of monitoring information, determining the source items
Jing Lijun, Chen Ruihui, Bai Xiaomei, Meng Fansheng, Yao Zhipeng, Teng Yanguo, Chen Haiyang   +6 more
doaj   +1 more source

Radio Frequency Fingerprint Identification Based on Deep Complex Residual Network

IEEE Access, 2020
Radio frequency fingerprint identification is a non-password authentication method based on the physical layer hardware of the communication device. Deep learning methods provide new ideas and techniques for radio frequency fingerprint identification. As
Shenhua Wang, Hongliang Jiang, Xiaofang Fang, Yulong Ying, Jingchao Li, Bin Zhang   +5 more
doaj   +1 more source

Source Identification of Asymptomatic Spread on Networks

IEEE Access, 2021
Identifying the sources of spreading dynamics on networks has drawn extensive attention in recent years, where a variety of epidemic models have been adopted to simulate the propagation dynamics among network nodes, such as the Susceptible-Infectious (SI)
Huan Liu, Qing Bao, Hongjun Qiu, Ming Xu, Benyun Shi   +4 more
doaj   +1 more source