Results 31 to 40 of about 88,848 (265)

Differences in marine hydrocarbon accumulation between the eastern and western parts of Shunbei area, Tarim Basin

Shiyou shiyan dizhi, 2023
From the eastern to the western part of Shunbei area in the Tarim Basin, the accumulations of marine oil and gas obviously decrease with the exploration risks significantly increasing.
Lixin QI, Yong DING
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Karakteristik Batuan Sumber (Source Rock) Hidrokarbon pada Formasi Batuasih di daerah Sukabumi, Jawa Barat

Indonesian Journal on Geoscience, 2014
http://dx.doi.org/10.17014/ijog.vol4no3.20092The purpose of the study carried out on the claystone of Batuasih Formation in Sukabumi area is to find out the hidrocarbon potential and its characteristics.
Praptisih Praptisih, Kamtono Kamtono, P. S. Putra, M. Hendrizan   +3 more
doaj   +1 more source

Detailed facies analysis of Cenomanian–Turonian organic‐rich mudstones: Implications for depositional controls on source rocks

The Depositional Record, 2020
Understanding mudstone depositional processes, including both traction transport and dynamic mechanisms, requires a re‐assessment of how these processes relate to the accumulation and preservation of organic carbon in fine‐grained successions.
Emma L. Percy, Per K. Pedersen
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Organic geochemical characters of source rock and significance for exploration of the Tumuxiuke Formation in Fuman area, Tarim Basin

地质科技通报
Objective As a newly discovered source rock in the Fuman area of the Tarim Basin, the source rock of the Tumuxiuke Formation has good petroleum exploration prospects, and the geochemical evaluation of the source rock is conducive to guiding exploration ...
Haijun YANG, Zhenzhong CAI, Yong LI, Xianzhang YANG, Yintao ZHANG, Yanqiu ZHANG, Chong SUN, Pengfei KANG, Haizu ZHANG, Xingxing ZHAO   +9 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Research of domanic source rock by pyrolytic gas chromatography-mass spectrometry method

Georesursy, 2019
We applied new novel approach based on pyrolytic gas chromatography-mass spectrometry technology (Py-GCMS) developed by Frontier Lab company (Japan) in order to get the same data as it can be acquired by using conventional core analyzer.
A.E. Chemodanov, B.I. Gareev, G.A. Batalin, R.S. Gerasimov   +3 more
doaj   +1 more source