Results 41 to 50 of about 97,380 (263)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Rock Physical Model and AVO Patterns for the Mud-Rich Source Rock

Frontiers in Earth Science, 2021
Rock physical model and amplitude variation with offset (AVO) patterns considering the content of organic matter and the composition of minerals have a wider significance for guiding the identification and prediction of the mud-rich source rock.
Songhe Yu, Songhe Yu, Zhaoyun Zong, Zhaoyun Zong, Xingyao Yin, Xingyao Yin   +5 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Sedimentary characterization of the carbonate source rock of Upper Kimmeridgian Parnac Formation of the Aquitaine Basin (Quercy area)

BSGF - Earth Sciences Bulletin, 2017
The main source rock (SR) of the Aquitaine Basin, the most important oil province in France, corresponds to organic-rich marine limestones of Upper Kimmeridgian age (Lons Formation in the Béarn area and Parnac Formation in the Quercy area).
Bastianini Laura, Caline Bruno, Hoareau Guilhem, Bonnel Cédric, Martinez Mathieu, Lézin Carine, Baudin François, Brasier Alexander, Guy Laurent   +8 more
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source

A Practical Noise2Noise Denoising Pipeline for High‐Throughput Raman Spectroscopy

Advanced Engineering Materials, EarlyView.
A lightweight and reproducible denoising pipeline for high‐throughput Raman spectroscopy is introduced, based on a 1D convolutional autoencoder trained with a Noise2Noise strategy. Using only repeated short‐exposure acquisitions, the method suppresses stochastic noise without reference spectra, enabling reliable spectral reconstruction while preserving
David Martin‐Calle, Cesar Alvarez‐Llamas, Vincent Motto‐Ros, Christophe Dujardin, Jérémie Margueritat, David Rodney   +5 more
wiley   +1 more source

High‐Entropy Alloy Interlayers Toward Advanced Joining for High‐Performance Structural Applications: Current Progress and Emerging Challenges

Advanced Engineering Materials, EarlyView.
HEA interlayers offer a versatile route for joining high‐performance structural materials. Their compositional and structural design regulates interfacial reactions, suppresses brittle IMCs, and improves metallurgical bonding. Sandwich interlayers further integrate defect healing with precipitation strengthening, enabling improved strength–ductility ...
Lin Yuan, Jiafen Song, Jinglong Li, Jiangtao Xiong, Tao Yang   +4 more
wiley   +1 more source

Genetic classification and geochemical evaluation of Upper Cretaceous carbonate reservoir oils in Dezful Embayment and Abadan Plain, SW Iran

Journal of Petroleum Exploration and Production Technology
The Upper Cretaceous carbonate reservoir oils from the Abadan Plain and Dezful Embayment in southwest Iran underwent analysis utilizing GC, GC-MS, and stable carbon isotope methods to elucidate the regional genetic oil family distribution.
Hossein Saadati, Ali Kadkhodaie, Mehrab Rashidi, Hossein Bahrami, Hashem Sarafdokht, Dmitriy A. Martyushev, Amir Abbass Jahangard   +6 more
doaj   +1 more source

Identification of Milankovitch Cycles and Their Sedimentary Responses in Fine-Grained Depositional Strata on the Southwestern Margin of the Songliao Basin

Applied Sciences
A series of fault depressions developed in the Kailu area on the southwestern margin of the Songliao Basin, where thick lacustrine fine-grained sedimentary rocks were widely deposited during the initial faulting stage in the Early Cretaceous.
Xuntao Yu, Xiuli Fu, Yunfeng Zhang, Yunlong Fu, Botao Huang, Jiapeng Yuan, Siyu Du   +6 more
doaj   +1 more source