Results 101 to 110 of about 10,574,194 (321)
EAI Endorsed Transactions on Context-aware Systems and Applications, 2018 This paper focuses on solving a challenging speech enhancement problem: improving the desired speech from a single-channel audio signal containing high-level unspecified noise (possibly environmental noise, music, other sounds, etc.).
Thanh Thi Hien Duong +2 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Shift-Invariant Kernel Additive Modelling for Audio Source Separation
, 2018 A major goal in blind source separation to identify and separate sources is to model their inherent characteristics. While most state-of-the-art approaches are supervised methods trained on large datasets, interest in non-data-driven approaches such as ...
Ewert, Sebastian +3 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Sparse Sources Are Separated Sources
, 2006 Publication in the conference proceedings of EUSIPCO, Florence, Italy ...
openaire +1 more source
A Convex Geometry-Based Blind Source Separation Method for Separating Nonnegative Sources [PDF]
IEEE Transactions on Neural Networks and Learning Systems, 2015 This paper presents a convex geometry (CG)-based method for blind separation of nonnegative sources. First, the unaccessible source matrix is normalized to be column-sum-to-one by mapping the available observation matrix. Then, its zero-samples are found by searching the facets of the convex hull spanned by the mapped observations.
Yang, Z., Xiang, Y., Rong, Yue, Xie, K.
openaire +3 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Spike sorting: the overlapping spikes challenge
Current Directions in Biomedical Engineering, 2015 When recording action potentials (spikes) from many neurons simultaneously via multichannel micro-electrodes the overlapping of spikes from different neurons is a demanding problem for detection and classifi-cation of spikes (spike sorting).
Sauer Inga +2 more
doaj +1 more source
Could Spin-Charge Separation be the Source of Confinement?
, 2005 Yang-Mills gauge field with gauge group SU(2) decomposes into a single charge neutral complex vector, and two spinless charged scalar fields. At high energies these constituents are tightly confined into each other by a compact U(1) interaction, and the ...
Niemi, Antti J.
core +3 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source