Results 81 to 90 of about 2,361,330 (284)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Simultaneous inactivation of antibiotic-resistant bacteria and degradation of antibiotic-resistant genes in alkalised human urine

Frontiers in Microbiology
The coexistence of pharmaceuticals and microorganisms in source separated urine poses a risk for the development of antimicrobial resistance (AMR), especially when urine-based fertilizers are applied to soils.
Natnael Demissie, Natnael Demissie, Annika Nordin, Prithvi Simha, Isis Conroy, He Sun, Anna Schnürer, Björn Vinnerås, Adey Desta, Adey Desta   +9 more
doaj   +1 more source

Concatenate Convolutional Neural Networks for Non-Intrusive Load Monitoring across Complex Background

Energies, 2019
Non-Intrusive Load Monitoring (NILM) provides a way to acquire detailed energy consumption and appliance operation status through a single sensor, which has been proven to save energy.
Qian Wu, Fei Wang
doaj   +1 more source

Iterative Receivers for Large-Scale MIMO Systems With Finite-Alphabet Simplicity-Based Detection

IEEE Access, 2020
In this paper, we consider large-scale MIMO systems and we define iterative receivers which use the simplicity-based detection algorithm referred to as Finite Alphabet Simplicity (FAS) algorithm.
Zahran Hajji, Karine Amis, Abdeldjalil Aissa El Bey   +2 more
doaj   +1 more source

Blind source separation of tensor-valued time series

, 2017
The blind source separation model for multivariate time series generally assumes that the observed series is a linear transformation of an unobserved series with temporally uncorrelated or independent components.
Nordhausen, Klaus, Virta, Joni
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Speech Segregation based on Pitch Track Correction and Music-Speech Classification

Advances in Electrical and Computer Engineering, 2012
A novel approach for pitch track correction and music-speech classification is proposed in order to improve the performance of the speech segregation system.
KIM, H.-G., JANG, G.-J., PARK, J.-S., KIM, J.-H., OH, Y.-H.   +4 more
doaj   +1 more source

Could Spin-Charge Separation be the Source of Confinement?

, 2005
Yang-Mills gauge field with gauge group SU(2) decomposes into a single charge neutral complex vector, and two spinless charged scalar fields. At high energies these constituents are tightly confined into each other by a compact U(1) interaction, and the ...
Niemi, Antti J.
core   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Majorization-Minimization Algorithm for Discriminative Non-Negative Matrix Factorization

IEEE Access, 2020
This paper proposes a basis training algorithm for discriminative non-negative matrix factorization (NMF) with applications to single-channel audio source separation.
Li Li, Hirokazu Kameoka, Shoji Makino
doaj   +1 more source