Results 81 to 90 of about 5,113,439 (297)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Speech Segregation based on Pitch Track Correction and Music-Speech Classification

Advances in Electrical and Computer Engineering, 2012
A novel approach for pitch track correction and music-speech classification is proposed in order to improve the performance of the speech segregation system.
KIM, H.-G., JANG, G.-J., PARK, J.-S., KIM, J.-H., OH, Y.-H.   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Iterative Receivers for Large-Scale MIMO Systems With Finite-Alphabet Simplicity-Based Detection

IEEE Access, 2020
In this paper, we consider large-scale MIMO systems and we define iterative receivers which use the simplicity-based detection algorithm referred to as Finite Alphabet Simplicity (FAS) algorithm.
Zahran Hajji, Karine Amis, Abdeldjalil Aissa El Bey   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Majorization-Minimization Algorithm for Discriminative Non-Negative Matrix Factorization

IEEE Access, 2020
This paper proposes a basis training algorithm for discriminative non-negative matrix factorization (NMF) with applications to single-channel audio source separation.
Li Li, Hirokazu Kameoka, Shoji Makino
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Acceptance of waste separation at source practice among households: a literature review [PDF]

, 2017
The successful of waste separation at source depends on the willingness and good practices among the residents. The participation rate of waste separation in Malaysia is low and there is an urgency to foster waste separation practice among the household.
Daud, Dzurllkanian @ Zulkarnain, Razali, Fitriyah, Choong, Weng Wai, Chin, Hon Choong   +3 more
core   +1 more source