Results 131 to 140 of about 587,175 (265)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Importance of R₂ accuracy in susceptibility source separation. [PDF]

Magn Reson Med
Oliveira Assunção TB, Naji N, Snyder J, Seres P, Blevins G, Smyth P, Wilman AH.   +6 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

A music source separation method integrating time-frequency decoupling and mamba-based state space modeling. [PDF]

Sci Rep
Zhang C, Zheng J, Cao M.
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Audio-visual source separation with localization and individual control. [PDF]

PLoS One
Kothandaraman M, Ramalingam B, Sheng K, Verma A, Dhagat U, Parab P, Mallavolu S, Ganesh S.   +7 more
europepmc   +1 more source

Functional Source Separation-Identified Epileptic Network: Analysis Pipeline. [PDF]

Brain Sci, 2022
Olejarczyk E, Zappasodi F, Ricci L, Pascarella A, Pellegrino G, Paulon L, Assenza G, Tecchio F.   +7 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Anisotropic local covariance matrices for spatial blind source separation. [PDF]

Adv Stat Anal
Muehlmann C, Cappello C, De Iaco S, Nordhausen K.   +3 more
europepmc   +1 more source

LOCUS: A REGULARIZED BLIND SOURCE SEPARATION METHOD WITH LOW-RANK STRUCTURE FOR INVESTIGATING BRAIN CONNECTIVITY. [PDF]

Ann Appl Stat, 2023
Wang Y, Guo Y.
europepmc   +1 more source