Results 111 to 120 of about 39,814,115 (303)
Ohio Retirement Study Council comparative performance study, period ending Dec. 31, 2002
, 2002 Semiannual; Nov. 13, 2000-; Title from cover of PDF document (viewed Feb. 13, 2006).; Vol. for 2002-2003 prepared by Milliman USA; vol. for 2004- prepared by Evaluation Associates.; Some vol. also called quarters.; Chronological designation based on date
Ohio Retirement Study Council
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
METHODOLOGICAL-COGNITIVE COLLAPSE IN THE MODERN HISTORY OF STATE AND LAW
Правовое государство: теория и практикаIn the modern history of state and law there is a situation that can be characterized as a methodological-cognitive collapse. The purpose of the study is to identify and characterize the main components of the methodologicalcognitive collapse in the ...
DEMICHEV Alexey Andreevich
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Open Source Software, Competition and Potential Entry [PDF]
We analyze a model with two software firms, quality improving coding expenditures and potential competition. The firms can publish parts of their software as open source.
Thorsten Wichmann, Pio Baake
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The Beatitudes: a Source-Critical Study
Novum Testamentum, 1983 C. M. Tuckett, M. D. Goulder
openaire +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Digital copies of «Instructive gospel» in manuscripts and early printed tradition
Библиосфера, 2012 The article introduces the results of works on digitalizing of outstanding old Russian manuscripts and early printed books which are carried out in the Rare book and Manuscript Department of SPSTL of SB RAS.
A. J. Borodikhin, A. V. Shabanov
doaj