Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Transfer learning for T-cell response prediction. [PDF]
BMC BioinformaticsStadelmaier J, Malone B, Eggeling R.
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Étudier la violence en Afrique : apport des sources, enjeux de terrain et considérations éthiques
Sources, 2021 Élodie Apard +1 more
doaj +1 more source
The value of adding 'grey literature' in evidence synthesis for equity-driven global health: a case study from Small Island Developing States. [PDF]
BMJ Glob HealthBrugulat-Panés A +6 more
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Eye movement desensitization and reprocessing treatment for birth trauma: a scoping review. [PDF]
Eur J PsychotraumatolO'Donovan S, Ward L, Melia R.
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
'I'm sure within 5 minutes I can find someone that will be selling it': qualitative insights into how social media facilitates the sale of banned flavoured tobacco products. [PDF]
Tob ControlSinger JM +4 more
europepmc +1 more source