Results 121 to 130 of about 6,052,198 (305)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Chicago Summer Institute 2013 - Evaluating Sources

, 2013
Why Sources Matter -- Spring 2012A PDF file of PowerPoint slides for the lesson "Why Sources Matter." Topic include: judging the reliability of sources, evaluating sources, independent sources, self-interested sources, multiple sources, single sources ...
Stony Brook University. School of Journalism. Center for News Literacy.
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Chicago Summer Institute 2013 - Why Sources Matter

, 2013
Evaluating Sources Student Slides Handout -- Fall 2013Student handouts for the lecture "Why Sources Matter." Topics include: IMVAIN, news outlets, news sources, reliability of sources, independent sources, self-interested sources, authoritive sources ...
Stony Brook University. School of Journalism. Center for News Literacy.
core  

Sources

, 2017
The sources for the geographic data (per species and ...
Shai Meiri (394933), Meiri, Shai, Uri Roll (282679), Bauer, Aaron, Anat Feldman (3246396), Grenyer, Richard, Novosolov, Maria, Feldman, Anat, Richard Grenyer (2917505), Maria Novosolov (3321609), Aaron Bauer (3980339), Roll, Uri   +11 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Evaluting Sources

, 2014
Transcript: 60 Minutes Piece from MatsushimaExcerpt from a report by CBS News "60 Minutes, Scott Pelley reporting on the aftermath of the Sendai earthquake and Tsunami.The $200 Million Myth -- cooper200milx264.mp4 Cop Shot -- copshotx264.mp4 Barbara ...
Pelley, Scott
core  

Viragem arquivística e viragem digital em África

Sources, 2020
Vincent Hiribarren
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source