Results 131 to 140 of about 6,052,198 (305)
La photographie, (res)source sensible pour les sciences sociales
Constance Perrin-Joly +1 more
doaj +1 more source
Computer technologies like computer languages and hardware have been involving for past few decades. We have a lot of computer programs which need to maintain and rewrite when releasing new equipment or technology. It is too expensive and unreliable to rewrite the whole code from scratch.
Evgeniy Ilyushin, Dmitry Namiot
openaire +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Savoirs environnementaux en Afrique : introduction au numéro
Luisa Arango +2 more
doaj +1 more source
Écrire l’histoire juridique de la folie en Afrique française (fin xixe siècle-1960)
The legal history of madness has long remained a marginal research subject within studies on French colonial law and justice in the nineteenth and twentieth centuries.
Silvia Falconieri
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Un journal à l’hôpital. Réformer la psychiatrie dans l’Algérie coloniale en guerre (1953-1959)
Between 1953 and 1959, the Blida-Joinville Psychiatric Hospital (HPB) published a weekly magazine with the sober title Notre Journal. It was written jointly by the colonial hospital’s patients, nursing staff and doctors, and was seen as the “social ...
Paul Marquis
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source

