Results 91 to 100 of about 7,194,405 (289)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Heath Network Clinicians Use and Need for Clinical Information Sources: Results of a Survey [PDF]

, 2018
The Dana Medical Library, part of the University of Libraries system, with the support of the University of Vermont Health Network, assessed the needs of UVM Health Network clinicians for evidence-based clinical resources such as: medical databases ...
Burke, Marianne, Light, Jeanene
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

How physicians perceive and utilize information from a teratogen information service: The Motherisk Program

BMC Medical Education, 2004
Background Teratogen information services have been developed around the world to disseminate information regarding the safety of maternal exposures during pregnancy. The Motherisk Program in Toronto, Canada, fields thousands of these inquiries per year.
Park Andrew, Einarson Adrienne, Koren Gideon   +2 more
doaj   +1 more source

The role of linked data and the semantic web in building operation [PDF]

, 2013
Effective Decision Support Systems (DSS) for building service managers require adequate performance data from many building data silos in order to deliver a complete view of building performance. Current performance analysis techniques tend to focus on a
Coakley, Daniel, Corry, Edward, Keane, Marcus, O'Donnell, James, Pauwels, Pieter   +4 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Photovoltaic power forecasting: A Transformer based framework

Energy and AI
The accurate prediction of photovoltaic (PV) energy production is a crucial task to optimise the integration of solar energy into the power grid and maximise the benefit of renewable source trading in the energy market.
Gabriele Piantadosi, Sofia Dutto, Antonio Galli, Saverio De Vito, Carlo Sansone, Girolamo Di Francia   +5 more
doaj   +1 more source

The infosource scale: a measure to assess the importance of external tourism information sources [PDF]

Information sources have long been considered an important variable in understanding consumer purchasing behaviors. Although research on information sources has been performed in a wide range of social disciplines, this variable has never been ...
Abrantes, Jose Luis, Lages, Luis Filipe, Seabra, Claudia   +2 more
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source