Results 101 to 110 of about 280,542 (312)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
REVIEW: MAKING STRENGTH CELLULAR GLASS
Nonconventional Technologies ReviewThe original non-conventional technique of preparing expanded bottle utilizing recycled bottle waste and a combination between glycerin in association with Na2SiO3 and Na2CO3, as liquid and respectively, solid expanding agents, was experimentally tested ...
Lucian Paunescu, Sorin Mircea Axinte
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
NONCONVENTIONAL TECHNIQUE TO MAKE BOROSILICATE GLASS FROTH
Nonconventional Technologies ReviewThe article shows testing outcomes of preparing a froth from residual borosilicate bottle utilizing lignite coal powder as an expanding agent in association with water glass to avoid premature pre-oxidation of carbon before reaching the sintering ...
Lucian Paunescu +2 more
doaj
LIGHTWEIGHT AGGREGATE FROM RECYCLED MASONRY RUBBLE ACHIEVED IN MICROWAVE FIELD
Nonconventional Technologies Review, 2019 The work refers to an innovative recycling solution of wastes from demolition and rehabilitation of buildings to produce more cost-effective lightweight aggregates.
Lucian Paunescu +3 more
doaj
The Determinants of Intra-Firm Trade [PDF]
This paper analyzes the determinants of the intra-firm vs arms’length sourcing mode of imported inputs. We build a unique French dataset of 1,141,393 import transactions at the firm, country and product levels in the year 1999 that allow us to ...
Delphine M. Irac +3 more
core
A Continuous Review Inventory System with Lost Sales and Emergency Orders [PDF]
, 2018 We analyze a continuous review lost sales inventory system with two types of orders—regular and emergency. The regular order has a stochastic lead time and is placed with the cheapest acceptable supplier. The emergency order has a deterministic lead time
Haughton, Michael, Isotupa, K.P. Sapna
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Nonconventional Technologies Review, 2019 The use of microwaves as a nonconventional energy source in the manufacturing process of glass-ceramic foam is presented in the paper. The main raw materials, representing 88wt.% of the load, are bottle glass waste and old clay brick waste, available in
Marius Florin Dragoescu +3 more
doaj
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source