Results 101 to 110 of about 284,563 (309)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

NONCONVENTIONAL TECHNIQUE TO MAKE BOROSILICATE GLASS FROTH

Nonconventional Technologies Review
The article shows testing outcomes of preparing a froth from residual borosilicate bottle utilizing lignite coal powder as an expanding agent in association with water glass to avoid premature pre-oxidation of carbon before reaching the sintering ...
Lucian Paunescu, Sorin Mircea Axinte, Bogdan Valentin Paunescu   +2 more
doaj  

Why do Firms Engage in Multi-sourcing? [PDF]

We provide an explanation for multi-sourcing, which is often found in the real world and refers to the situation where a final goods producer acquires homogenous components from different suppliers.
Arijit Mukherjee, Justin Yifu Lin, Yingyi Tsai   +2 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Competition and Technological Complexity in Procurement: An Empirical Study of Dual Sourcing [PDF]

The role of competition in defense procurement has long been controversial due to the extraordinary demand for technological advance, the relatively small production quantities involved and the importance of learning by doing.
Thomas P. Lyon
core  

Underdetermined Source Separation For Colored Sources

, 2006
Publication in the conference proceedings of EUSIPCO, Florence, Italy ...
Stefan Winter 0002, Walter Kellermann, Hiroshi Sawada, Shoji Makino   +3 more
openaire   +4 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

LIGHTWEIGHT AGGREGATE FROM RECYCLED MASONRY RUBBLE ACHIEVED IN MICROWAVE FIELD

Nonconventional Technologies Review, 2019
The work refers to an innovative recycling solution of wastes from demolition and rehabilitation of buildings to produce more cost-effective lightweight aggregates.
Lucian Paunescu, Marius Florin Dragoescu, Sorin Mircea Axinte, Ana Casandra Sebe   +3 more
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source