Results 71 to 80 of about 280,542 (312)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
INNOVATIVE WAY TO PRODUCE GLASS FOAM IN MICROWAVE FIELD
Nonconventional Technologies Review, 2018 The paper presents results of research conducted by the Romanian company Daily Sourcing & Research on the use of microwave energy in the manufacture process of glass foams.
Lucian Paunescu +3 more
doaj
Swedish teenagers’ difficulties and abilities to determine digital news credibility
Nordicom Review, 2019 In this study we investigate the abilities to determine the credibility of digital news among 483 teenagers. Using an online survey with a performance test we assess to what extent teenagers are able to determine the credibility of different sources ...
Nygren Thomas, Guath Mona
doaj +1 more source
Capacity Reservation under Spot Market Price Uncertainty [PDF]
The traditional way of procurement, using long-term contract and capacity reservation, is competing with the escalating global spot market. Considering the variability of the spot prices, the flexibility of combined sourcing can be used to benefit from ...
Karl Inderfurth, Peter Kelle
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
NONCONVENTIONAL HEATING METHOD USED TO OBTAIN GLASS FOAM FROM CLEAR FLAT GLASS WASTE
Nonconventional Technologies Review, 2018 Results of the research conducted by the Romanian company Daily Sourcing & Research Bucharest to obtain glass foams from clear flat glass waste with good macrostructural homogeneity are presented in the paper.
Marius Florin Dragoescu +2 more
doaj
Sourcing efficacy – The role of supportive intelligence
Ekonomski VjesnikPurpose: Globalization has increased the importance of sourcing and procurement strategies and factbased negotiation (FBN). Technological advances such as machine learning (ML) and artificial intelligence (AI) and their integration in FBN are significant
Aleksandar Erceg, Santhosh Joseph
doaj +1 more source
DOMESTIC AND GLOBAL SOURCING [PDF]
This paper develops a general equilibrium Ricardian model with transaction costs to investigate the determinants of the firm's sourcing decision. It derives conditions under which different sourcing choices and corresponding trade patterns occur in ...
Dingsheng Zhang, Wenli Cheng
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
We present a North—South model of international trade in which differentiated products are developed in the North. Sectors are populated by final-good producers who differ in productivity levels.
Elhanan Helpman, Pol Antras
core