Results 101 to 110 of about 112,180 (254)
Advanced Science, EarlyView.A novel strategy features gradient composition and stacking fault energy‐tuned (CoCrMn)100‐2xFexNix fabricated via in situ alloying additive manufacturing. This design circumvents cryogenic discontinuous plastic flow and hydrogen embrittlement of metallic materials under quasi‐static loading and hydrogen‐rich environment relevant to lunar polar ...
Renhao Wu +11 more
wiley +1 more source
South-South cooperation as a mechanism to strengthen public health services in Africa: experiences, challenges and a call for concerted action. [PDF]
Pan Afr Med J, 2017 Olu O +3 more
europepmc +1 more source
Advanced Science, EarlyView.Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng +15 more
wiley +1 more source
Beyond Probiotics: Postbiotics for Healthy Aquaculture
Advanced Science, EarlyView.This critical review assesses limitations of probiotics and proposes postbiotics, preparations of inanimate microorganisms and their metabolites, as a more stable, controlled, and biosafe formulation. Postbiotics offer significant advantages during industrial aquafeed production and storage. However, their practical implementation is currently hindered
Michael Leonidas Chikindas +12 more
wiley +1 more source
O Brasil e a construção de uma fábrica de medicamentos em Moçambique
Meridiano 47, 2017 This work investigates the goals of Brazil from the implementation of a pharmaceutical plant in Mozambique. Interviews with authorities involved in the construction of the plant and documentary analysis of official publications was performed. The results
Tiago Severo Garcia +1 more
doaj
Liquid‐Responsive Shape‐Memory Nanofiber‐Reinforced Scaffolds for Cartilage Repair
Advanced Science, EarlyView.A liquid‐responsive shape‐memory, nanofiber‐reinforced QCG scaffold combines conformal defect filling, an aligned architecture that is structurally permissive for endogenous cell infiltration, and sustained KGN release. This integrated design enhances BMSC viability, migratory activity, and chondrogenic differentiation and promotes hyaline cartilage ...
Jiyang Zeng +8 more
wiley +1 more source
International Journal of Communication, 2016 The impact of BRICS (Brazil, Russia, India, China, and South Africa) and other emerging economies on the field of international development has seen traditional donor nations wrestle with fundamental shifts in the geometry and makeup of the donor ...
James Pamment, Karin Wilkins
doaj
Advanced Science, EarlyView.The schematic diagram depicts a compartmentalized anti‐ferroptotic defense mechanism mediated by GSTA4. GSTA4 is upregulated and localizes to the cytoplasm in ENZR cells, where it detoxifies 4‐HNE via a non‐canonical GSH‐dependent pathway. Under oxidative stress, GSTA4 translocates to mitochondria, interacts with PGAM5, and blocks Drp1 Ser637 ...
Yong Luo +17 more
wiley +1 more source
Advanced Science, EarlyView.Upon cigarette smoke exposure(CSE), LDHA expression is increased in lung macrophages, promoting the conversion of pyruvate to lactate and elevating the lactylation level of SP1 at the K694 site. This, in turn, enhances SP1 enrichment at the TREM1 promoter, increases TREM1 expression, promoted M1 macrophage polarization, and triggers the secretion of ...
Ling Lin +5 more
wiley +1 more source