Results 111 to 120 of about 3,221,844 (374)

Dual Targeting of Mutant p53 and SNRPD2 via Engineered Exosomes Modulates Alternative Splicing to Suppress Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Mutant p53 drives oncogenic splicing to promote the progression of ovarian cancer by partnering with the spliceosome factor SNRPD2. Therefore, it is engineered iRGD‐exosomes to co‐deliver siRNAs against both targets. This approach restored tumor‐suppressive mRNA isoforms, effectively enhanced sensitivity to cisplatin, and ultimately blocked tumor ...
Wei Zhao   +14 more
wiley   +1 more source

Boron Nitride Reinforced Supramolecular Gels Nano‐Assembled with Fungicides toward Soil‐Borne Fungal Disease Management

open access: yesAdvanced Science, EarlyView.
This work demonstrates of 2D material‐mediated stimuli‐responsive transport in soft matter systems, pioneers a new class of nano‐bridged carriers with mechanically strengthening and programmable permeability characteristics designed to overcome persistent barriers in soil‐borne disease management.
Li Hao   +9 more
wiley   +1 more source

Economic regional and cross-border cooperation in the South-East Europe for the purpose of its faster integration in the European Union [PDF]

open access: yes, 2004
Territorial borders of the future European Union imply an integration of the South-East Europe into the EU political and economic structures. Such “map of the European Union” should represent the “European perspective” to the countries of the South-East ...
Ibreljic, Izet, Kulenovic, Salih
core  

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

open access: yesAdvanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang   +12 more
wiley   +1 more source

Defect Engineering Activates Pyrene‐Based Covalent Organic Frameworks for Efficient Photocatalytic Uranium Capture

open access: yesAdvanced Science, EarlyView.
A defect‐engineered pyrene‐based covalent organic framework (TP‐PYTO‐SA) is developed via strategic salicylaldehyde incorporation. This approach simultaneously enhances hydrophilicity and introduces uranyl coordination sites, while optimized defect density significantly improves charge separation.
Weikun Yao   +5 more
wiley   +1 more source

Cooperation between Latin America and Asia-Pacific region in the Framework of South-South Cooperation as a New Dimension of International Relations

open access: yesУправленческое консультирование, 2018
This article deals with analysis of South-South cooperation in a view of its intensification in recent times. The author focuses on the processes of interregional cooperation between the two emerging regions, Latin America and Asia Pacific region, as ...
Anna Borisovna Molodtcova   +1 more
doaj  

South-south cooperation on tobacco control - Project Plan on Article 5.2. National Coordination Brasil - Colombia

open access: yesTobacco Induced Diseases, 2018
Background and challenges to implementation Based on Colombian demands to meet its obligations under the WHO FCTC and face the challenges on strengthening and accelerating tobacco control programs, both countries set a Cooperation Project aimed to raise ...
Diogo Alves   +1 more
doaj   +1 more source

Clickable Microgel Inks Enable Spatioselective, Multi‐Stimuli Programmable Assembly of Materials

open access: yesAdvanced Science, EarlyView.
Clickable microgel inks enable direct ink writing of hydrogel architectures with intrinsic spatioselective and programmable multi‐responsiveness. By combining pH‐responsive and temperature‐responsive microgel building blocks through Diels‐Alder interparticle crosslinking, the assemblies exhibit controllable swelling and shape changes.
Junho Moon   +3 more
wiley   +1 more source

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