Results 41 to 50 of about 138,013 (260)

ON THE EVE OF BAPA+40 - SOUTH-SOUTH COOPERATION IN TODAY’S GEOPOLITICAL CONTEXT

open access: yesVestnik RUDN. International Relations, 2018
The “South-South cooperation” concept is still not widely known or used, except in the framework of the United Nations. Yet, its inception goes back more than 60 years, when the idea was crystallized as a key building bloc of the national liberation and ...
Branislav Gosovic
doaj   +1 more source

South Asia SDG update [PDF]

open access: yes, 2019
We are pleased to share the January 2019 issue of the South Asia SDG Update. The issue begins with a briefing on UNESCAP's activities in South Asia subregion for September-December 2019.
UN.ESCAP   +1 more
core  

The Future of Research in Cognitive Robotics: Foundation Models or Developmental Cognitive Models?

open access: yesAdvanced Robotics Research, EarlyView.
Research in cognitive robotics founded on principles of developmental psychology and enactive cognitive science would yield what we seek in autonomous robots: the ability to perceive its environment, learn from experience, anticipate the outcome of events, act to pursue goals, and adapt to changing circumstances without resorting to training with ...
David Vernon
wiley   +1 more source

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

open access: yesAdvanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao   +16 more
wiley   +1 more source

South-South Cooperation: Brazilian experiences in South America and Africa

open access: yesHistória, Ciências, Saúde: Manguinhos, 2015
Over recent years Brazil has played an increasingly active role internationally, the result of its model of integration and its foreign policy directives.
Roberta de Freitas Santos   +1 more
doaj   +1 more source

Molecular Glue cc‐885 Inhibits VHL‐Deficient Clear Cell Renal Cell Carcinoma via ETS1 Degradation

open access: yesAdvanced Science, EarlyView.
VHL‐deficient kidney cancer lacks effective treatments. This study reveals that the molecular glue degrader cc‐885 hijacks the cellular recycling system to selectively destroy the oncogenic protein ETS1, effectively killing VHL‐mutant tumors. Combining CC‐885 with the approved drug belzutifan achieves powerful synergy, offering a promising new ...
Taowei Yang   +15 more
wiley   +1 more source

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

open access: yesAdvanced Science, EarlyView.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li   +13 more
wiley   +1 more source

Varying Presence, Diverging Approaches: The influence of the emerging powers on health cooperation in Mozambique

open access: yesCadernos de Estudos Africanos, 2018
In the last decade the rising powers have received increased attention from policy makers, academicians and development practitioners. Notwithstanding claims about their importance for development cooperation, there is little tangible and evidence-based ...
Tom De Bruyn
doaj   +1 more source

Economic Contribution Analysis of South Carolina’s Forestry Sector, 2017 [PDF]

open access: yes, 2017
South Carolina’s forests are one of the foundations of the state’s economy and define its natural resource environment. They represent the dominant landscape of the state, and support many important manufacturing industries.
Willis, David B.   +3 more
core  

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

open access: yesAdvanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li   +15 more
wiley   +1 more source

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