Results 71 to 80 of about 1,194,169 (280)

Brazilian and Chinese Cooperation in African Agriculture. A Practice-based Study

open access: yesÍconos, 2013
In this article we analyze Brazilian and Chinese practices in terms of cooperation in Africa, focusing on the agricultural sector. While a great deal of work has analyzed the engagement of these emerging players from an international relations ...
Frédéric Goulet   +2 more
doaj   +1 more source

Economic regional and cross-border cooperation in the South-East Europe for the purpose of its faster integration in the European Union [PDF]

open access: yes
Territorial borders of the future European Union imply an integration of the South-East Europe into the EU political and economic structures. Such “map of the European Union” should represent the “European perspective” to the countries of the South-East ...
Izet Ibreljic, Salih Kulenovic
core  

Substantially Altered Local and Systemic Immunity in Ischemia‐Free Versus Conventional Liver Transplantation

open access: yesAdvanced Science, EarlyView.
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo   +40 more
wiley   +1 more source

Science Diplomacy and COVID-19: Future Perspectives for South-South Cooperation. [PDF]

open access: yesGlob Policy, 2022
Sharma J   +5 more
europepmc   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang   +9 more
wiley   +1 more source

Dual Targeting of Mutant p53 and SNRPD2 via Engineered Exosomes Modulates Alternative Splicing to Suppress Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Mutant p53 drives oncogenic splicing to promote the progression of ovarian cancer by partnering with the spliceosome factor SNRPD2. Therefore, it is engineered iRGD‐exosomes to co‐deliver siRNAs against both targets. This approach restored tumor‐suppressive mRNA isoforms, effectively enhanced sensitivity to cisplatin, and ultimately blocked tumor ...
Wei Zhao   +14 more
wiley   +1 more source

Money and South-South Cooperation

open access: yes, 1992
Monetary arrangements may sound technical and of subsidiary significance. The production and distribution of goods and services are what matter for the pattern of development. From this perspective it would appear that the important international arrangements are those that regulate flows of goods and services and of investment, technology and labour ...
openaire   +3 more sources

Engineering Compact Base Editors by AlphaFold‐Guided Mutation Scan and Escherichia coli‐Based Tri‐Selection

open access: yesAdvanced Science, EarlyView.
A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son   +2 more
wiley   +1 more source

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