Results 91 to 100 of about 2,620,083 (303)
Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
A 10,000 Mississippi Kite flock observed in Fuerte Esperanza, Argentina [PDF]
, 2006 The Mississippi Kite (Ictinia mississippiensis) is a Neotropical migrant that nests singly or in loose, small colonies in North America from North Carolina and north Florida west to Kansas, southeastern Colorado, and Texas and north along Mississippi ...
Areta, Juan Ignacio, Seipke, Sergio H.
core +1 more source
First Records of \u3ci\u3eGomphaeschna Furcillata\u3c/i\u3e and \u3ci\u3eAnax Longipes\u3c/i\u3e in Wisconsin (Odonata: Aeshnidae) [PDF]
, 2017 (excerpt) The two new records of Odonata reported here for Wisconsin are north- western range extensions for each species. The genus Gomphaeschna Selys contains two species, antilope (Hagen) and furcillata (Say), the distributions of which are limited to
Tennessen, K. J
core +2 more sources
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Annals of Clinical and Translational Neurology, EarlyView.Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
Publicación Electrónica de la Asociación Paleontológica Argentina, 2015 Paleogeographic reconstructions hypothesize that during the Cretaceous, South America was split into northern and southern portions by an epeiric seaway. Although the location, extent, and duration of this ancient seaway is debated, some propose that the
Gregory P. Wilson, Nan Crystal Arens
doaj
Water pollution in atlantic rainforest (south america) [PDF]
, 2015 Water contamination proves to be one of the most concerning human effects on the environment. Industry, urbanization and agriculture often introduce various pollutants including heavy metals, bacteria, agrochemicals, and drugs.
Avigliano, Esteban
core
Future large hydropower dams impact global freshwater megafauna [PDF]
, 2019 Dam construction comes with severe social, economic and ecological impacts. From an ecological point of view, habitat types are altered and biodiversity is lost.
Berlekamp, Juergen +5 more
core +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg +20 more
wiley +1 more source