Results 171 to 180 of about 2,620,083 (303)

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

Advanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu, Guoying Wang, Yang Zhang, Bingyang Shi, Ming Li   +4 more
wiley   +1 more source

Climate-driven changes in zoonotic risk of arenaviral hemorrhagic fevers in South America. [PDF]

Npj Viruses
Kulkarni PS, Flores-Pérez NY, Jian AH, Bird BH, Johnson CK, Uhart M, Pandit PS.   +6 more
europepmc   +1 more source

Impact of the Global Financial Crisis on Migration and Remittances [PDF]

Remittances to developing countries are estimated to have declined by 6.1 percent in 2009 as a result of weak job markets in major destination countries. Although new migration has fallen, it is still positive.
Mohapatra, Sanket, Ratha, Dilip
core  

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Advancing Wildlife Conservation Through Biobanking in South America. [PDF]

Animals (Basel)
Madelaire CB, Pereira AF, Sestelo AJ, Bom-Conselho AP, Vaj C, Mosalve FC, Brandão-Souza LS, Tavares MR, Rodriguez MD, Restrepo RO, Leite RF, Locatelli Y, Deco-Souza T, Araujo GR.   +13 more
europepmc   +1 more source

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source

PrEP public policies for HIV prevention in South America: an intersectional analysis. [PDF]

BMC Public Health
de Oliveira KH, de Oliveira Ferreira B, da Silva Junior FJ, Barp LFG, de Menezes Guerra CB, da Silva Câmara FD, de Almeida Soares MA, Bercht G, Honorato IB, Gagliolo AA, García MG, Dos Reis RP, Passamani GR, Kauss BS, Vallejo FR, Hurtado JCA, das Neves ALM.   +16 more
europepmc   +1 more source

Soft Neural Interfaces for Circuit‐Level Analysis of Magnetogenetic Deep Brain Stimulation in Parkinson's Disease Models

Advanced Healthcare Materials, EarlyView.
ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee, Yeongdo Lee, Enji Kim, Hunkyu Seo, Myoungjae Oh, Hanho Joo, Somin Lee, Jae‐Hyun Lee, Hyun Ho Jung, Minsuk Kwak, Jang‐Ung Park   +10 more
wiley   +1 more source

Spiro‐Phenothiazine Hole‐Transporting Materials: Unlocking Stability and Scalability in Perovskite Solar Cells

Advanced Materials, EarlyView.
Fluorene‐functionalized spiro‐phenothiazine (PTZ‐Fl) exhibits strong Li+ affinity and thermal stability, enabling a PCE of 25.75% in small‐area cells and 22.07% in 25 cm2 modules. Under ISOS‐L3 conditions, PTZ‐Flbased devices retain over 80% efficiency after 1000 hours, demonstrating superior stability and scalability compared to spiro‐OMeTAD for next ...
Javier Urieta‐Mora, Seung Ju Choi, Jaeki Jeong, Silvia Orecchio, Inés García‐Benito, Manuel Pérez‐Escribano, Joaquín Calbo, Likai Zheng, Minseop Byun, Seyeong Song, Gi‐Hwan Kim, Shaik M. Zakeeruddin, Seog‐Young Yoon, Yimhyun Jo, Agustín Molina‐Ontoria, Enrique Ortí, Nazario Martín, Michael Grätzel   +17 more
wiley   +1 more source

Human Infection by Zoonotic Eye Fluke Philophthalmus lacrymosus, South America. [PDF]

Emerg Infect Dis
Weitzel T, Cordero EM, Mujica T, Aravena C, Phillips BE, Yabsley MJ, Lewbart GA, Páez-Rosas D, Jercic MI, Capasso S.   +9 more
europepmc   +1 more source