Results 241 to 250 of about 2,620,083 (303)

New morphological features and phylogenetic insights of <i>Dioctophyme renale</i> from wild carnivores and a domestic dog in South America. [PDF]

Int J Parasitol Parasites Wildl
Gomes APN, Maldonado A, Olifiers N, Bueno C, Vilela RDV, Simões RO, Chambarelli MCMDC, Miranda K, Lopes-Torres EJ.   +8 more
europepmc   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

The Hydradephaga (Coleoptera, Dytiscidae, Gyrinidae, Haliplidae, Noteridae) of the Iberá wetlands, the second largest wetland area of South America. [PDF]

Zookeys
Urcola MR, Urcola JI, Michat MC, Torres PLM.   +3 more
europepmc   +1 more source

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

Advanced Science, EarlyView.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

Subterranean Biodiversity on the Brink: Urgent Framework for Conserving the Densest Cave Region in South America. [PDF]

Animals (Basel)
Zampaulo RA, Souza-Silva M, Ferreira RL.
europepmc   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Identification of Co-Circulating Dengue and South America-Origin Zika Viruses, Pakistan, 2021-2022. [PDF]

Emerg Infect Dis
Iqbal NT, Sawatzki K, Ahmed K, Tisoncik-Go J, Smith E, Voss K, Cornelius J, Wang L, Spaulding AB, Serebryannyy L, Douek DC, Syed MA, Mahmood SF, Khan E, Van Voorhis WC, Gale M.   +15 more
europepmc   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Justice enablers of climate-health adaptation in South America. [PDF]

J Clim Chang Health
Rekers R, Gerbaldo MV, Yabar C, Rodríguez Garat C, Rekers L.   +4 more
europepmc   +1 more source

SC-PREC4SA: A serially complete daily precipitation dataset for South America. [PDF]

Sci Data
Huerta A, Serrano-Notivoli R, Brönnimann S.   +2 more
europepmc   +1 more source