Results 231 to 240 of about 5,739,535 (364)

First morphological description of the larval stages of three <i>Microtendipes</i> species (Diptera, Chironomidae) from South China with molecular confirmation. [PDF]

Zookeys
Jin H, Wang Y, Song C, Qi X.
europepmc   +1 more source

Melatonin Modulates Glucose Metabolism Reprogramming via Targeting G6PD to Alleviate Lead‐Induced Hepatocytes Pyroptosis in Common Carp (Cyprinus carpio L.)

Advanced Science, EarlyView.
This study reveals that Lead reprograms glucose metabolism to enhance H3K18la, driving DRP1‐dependent mitochondrial DNA leakage and cGAS‐STING‐mediated pyroptosis. Melatonin targets G6PD to suppress glycolysis‐driven H3K18la and restore mitochondrial homeostasis, thereby alleviating Lead‐induced liver injury in common carp through disruption of the ...
Zhiying Miao, Xiaofeng Ji, Lai Wei, Zhiruo Miao, Shiwen Xu   +4 more
wiley   +1 more source

Virome diversity in small mammals from south China: Insights into virus evolution, transmission, and ecology. [PDF]

Virol Sin
Shi Y, Fang L, Li C, Li P, Liu J, Chen Y, Zhao Y, Li Z, Liu S, Ding Y, Zhou X, Jiang D, Shen J, Zhang Z, Lyu J, Pu R, Tan X, Yin J, Shi W, Cao G.   +19 more
europepmc   +1 more source

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

Advanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang, Hengxiang Zhang, Yuqi Zhou, Chunying Li, Weinan Guo   +4 more
wiley   +1 more source

Temporal, Spatial and Prey Niche Partitioning Reveals Coexistence Mechanism of Mesocarnivores in Guangdong Province, South China. [PDF]

Ecol Evol
Wu F, Hua Y, Dou H, Zhang Y, Dong X, Zhu D, Gao H.   +6 more
europepmc   +1 more source

Hepatitis E Virus ORF1 Polyprotein Harbors a Pocket‐Like Cavity That Is Vital for Virus Replication and Represents a Novel Antiviral Target

Advanced Science, EarlyView.
Within the hepatitis E virus (HEV) ORF1 polyprotein, the X domain interacts with viral RNA‐dependent RNA polymerase (RdRp), forming a functional “pocket‐like” cavity (PC) that is crucial for viral replication. Structure‐based screening, surface plasmon resonance (SPR) assays, and HEV model validation collectively identify saikosaponin D and ...
Xiaohui Ding, Dou Zeng, Dan Liu, Yingying Bian, Bin Li, Zheng Li, Qiudi Li, Shiquan Liang, Yunlong Si, Qili Yao, Yibo Ding, Jiahui Zhu, Xiangyang Li, Kuiyang Zheng, Hongbo Guo, Wenshi Wang   +15 more
wiley   +1 more source

A dual water isotope dataset for quantifying summer water mass transport in the northern South China Sea. [PDF]

Sci Data
Liu S, Chen C, Lu X, Wu J, Lao Q, Cai S, Chen F.   +6 more
europepmc   +1 more source

Detrital zircon provenance of the Paleogene syn‐rift sediments in the northern South China Sea

, 2016
L. Shao, Licheng Cao, X. Pang, T. Jiang, P. Qiao, Meng Zhao   +5 more
semanticscholar   +1 more source

A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing

Advanced Science, EarlyView.
This study discoveries that EBV EBNA1 behaves as a prion‐like protein, verified using cell‐based assays and the Saccharomyces cerevisiae Sup35p prion identification system. The prion‐like domain of EBNA1 drives liquid–liquid phase separation. EBNA1 interacts with the splicing factor SRSF1 to regulate the expression of the SRRM1 splicing isoforms ...
Xiaoyue Zhang, Zhengshuo Li, Run Zheng, Xiang Zheng, Jia Wang, Can Liu, Yangge Wu, Yuqing Wen, Chunlin Ou, Songqing Fan, Chenxiao Xu, Junrui Tian, Qun Yan, Hao Nan, Xiaodong Xu, Hui Wang, Qiu Peng, Jian Ma   +17 more
wiley   +1 more source