Results 31 to 40 of about 3,182,781 (295)

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Intracontinental deformation in southern Africa during the late Cretaceous [PDF]

, 2014
Intracontinental deformation accommodated along major lithospheric scale shear zone systems and within associated extensional basins has been well documented within West, Central and East Africa during the Late Cretaceous.
Gleadow, Andrew, Summerfield, Michael, Brown, Roderic, Gallagher, Kerry, Carter, Andrew, Gallagher, K., Summerfield, Michael A., Brown, Roderick, Summerfield, M., Beucher, R., Beucher, Romain, Brown, R., Gleadow, A., Wildman, M., Wildman, Mark   +14 more
core   +1 more source

Innovative development financing amidst uncertainty: how can African countries leverage domestic resource mobilization?

Journal of Economic Structures
In achieving the African Union Agenda 2063—The Africa We Want—and financing SDGs, African economies will require an unprecedented mobilization of resources.
Sodiq Arogundade, Maria Ngarachu, Olayinka Bandele   +2 more
doaj   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Impact of Titanium Mining and Other Anthropogenic Activities on Malaria Positivity Rates and Parasitemia in Five Selected Study Sites in Msambweni Subcounty, Kwale County, Kenya

Journal of Parasitology Research
Africa was home to 95% of malaria cases and deaths in 2021. The negative impacts of malaria can be aggravated by social–economic–environmental factors, more so agroeconomic practices such as irrigation, mining, and dam construction. The aim of this study
Edward Githinji, Collins Okoyo, Cassian Mwatele, Juma Mwatasa, Benard Chieng, Sylvie Araka, Henry Kanyi, Sammy Njenga, Judy Mwai   +8 more
doaj   +1 more source

Productive capacity and regional value chains of the automotive sector in Southern Africa

Cogent Economics & Finance
Southern Africa is one of the major suppliers of raw materials necessary for the automotive sector’s supply chain. However, the region remains far behind in integrating into the global supply chain, with the exception of South Africa.
Sodiq Arogundade, Olayinka Bandele, Vanessa Nakayange, Talumba Chilipaine   +3 more
doaj   +1 more source

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab, Evelyn Alvarez, Roua Hamdi, Bingqing Zhang, Hayeun Ji, Niyati Jhaveri, Patrick Schindler, Pedro Sanchez, Pia S. Sperber, Tanja Schmitz‐Hübsch, Frederike C. Oertel, Nisa Vorasoot, Najib Kissani, Falko Böhringer, Jens Kuhle, Anne‐Katrin Pröbstel, Xiao‐Jun Ma, Péter Körtvelyessy, Patrick Waters, Friedemann Paul   +19 more
wiley   +1 more source

A comparative analysis of landfill policies and regulatory frameworks in Southern African countries

Discover Sustainability
Landfilling remains a dominant waste disposal method in Southern Africa, despite its detrimental environmental and health impacts. Effective landfill policies and regulatory frameworks are crucial for mitigating these impacts.
Brian Nyathi
doaj   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

A critical analysis of regional integration in southern Africa [PDF]

, 1994
The collapse of state communism in Eastern Europe during the second half of the past decade and the subsequent demise of autocratic regimes in Africa presented the people of Southern Africa with new challenges that have become increasingly entangled in ...
Chiroro, Bertha
core