Results 41 to 50 of about 117,326 (185)

Genome-wide analysis of unrecognised ethnic group Chuanqing people revealing a close affinity with Southern Han Chinese

open access: yesAnnals of Human Biology, 2020
Background Chuanqing is an unrecognised ethnic group in Guizhou, southwest China. The genetic history of the Chuanqing people is hotly debated due to a lack of available genetic data.
Jiani Lu   +13 more
doaj   +1 more source

Forensic features and genetic structure of 20 autosomal STR loci in the Han population of Ningde City, Southeastern China

open access: yesAnnals of Human Biology, 2021
Background Short tandem repeat (STR) loci are widely used in forensic medicine and population genetics. Aim To profile 20 autosomal STR loci using the SureID® 21 G Human STR Identification Kit.
Hongbo Wang, Cairui Xin, Hongyi Cao
doaj   +1 more source

Age estimation in three distinct east Asian population groups using southern Han Chinese dental reference dataset

open access: yesBMC Oral Health, 2019
Background Dental age estimation can assist in the identification of victims following natural disasters and it can also help to solve birth date disputes in individuals involved in criminal activities.
Jayakumar Jayaraman   +8 more
doaj   +1 more source

Predominant frequency of HLA‐B*27 in patients with ankylosing spondylitis in southeastern China

open access: yesImmunity, Inflammation and Disease, 2021
Objectives This study was to investigate the polymorphism and distribution of alleles of HLA‐B*27 in patients with ankylosing spondylitis (AS) in Han population of southeastern China.
JiaoJiao Lu   +7 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Analysis of apolipoprotein E genetic polymorphism in a large ethnic Hakka population in southern China

open access: yesGenetics and Molecular Biology, 2018
There is currently no data about the genetic variations of APOE in Hakka population in China. The aim of this study was to analyze the allelic and genotypic frequencies of APOE gene polymorphisms in a large ethnic Hakka population in southern China.
Zhixiong Zhong   +3 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

Minority languages of China [PDF]

open access: yes, 2010
This chapter looks at language endangerment in the People's Republic of China, focusing on three of the main factors that influence language maintenance in China today: increased contact due to population movements and changes in the economy; the ...
LaPolla, Randy J., Poa, Dory
core  

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, Accepted Article.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among long‐term HCQ users with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain OCT (SD‐OCT) for screening. Methods A systematic search of PubMed, Scopus,
Narsis Daftarian   +4 more
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients with Extra‐Renal Systemic Lupus Erythematosus – A Systematic Review & Meta‐analysis

open access: yesArthritis Care &Research, Accepted Article.
Background Clinical response to Mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with SLE, particularly those with extra‐renal ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

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